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Protein Alignment eIF4E3 and EIF4E2

DIOPT Version :9

Sequence 1:	NP_648194.1	Gene:	eIF4E3 / 38923	FlyBaseID:	FBgn0265089	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_004837.1	Gene:	EIF4E2 / 9470	HGNCID:	3293	Length:	245	Species:	Homo sapiens

Alignment Length:	178	Identity:	63/178 - (35%)
Similarity:	104/178 - (58%)	Gaps:	21/178 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KHPLEHTWTLWHLENDRT-------KRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMV 123
            :|||::.:|.|:  :.||       :.:.:.:..:.:|.:||.|:..|..:..|.||...:|:.:
Human    53 EHPLQYNYTFWY--SRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHL 115

  Fly   124 FKKNIRPMWEDDTNKNGGRWILLLDK--ASRTYIDKMWHDLLLCMIGECFQHSDEICGVVINVRN 186
            ||:.|:||||||.|||||:||:.|.|  |||     .|.:|:|.|:||.|...:||||.|::||.
Human   116 FKEGIKPMWEDDANKNGGKWIIRLRKGLASR-----CWENLILAMLGEQFMVGEEICGAVVSVRF 175

  Fly   187 KANKLSLWTKDSRNVEAILSIGRQIKELLHL---GIMEIQYQVHKDAM 231
            :.:.:|:|.|.:.:......|...::.:|:|   .|||  |:.|.|::
Human   176 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIME--YKTHTDSI 221

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.