Protein Alignment eIF4E3 and CDC33

DIOPT Version :9

• Sequence 1: NP_648194.1
• Gene: eIF4E3 / 38923
• FlyBaseID: FBgn0265089
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_014502.1
• Gene: CDC33 / 854026
• SGDID: S000005499
• Length: 213
• Species: Saccharomyces cerevisiae
• Alignment Length: 176
• Identity: 67/176 - (38%)
• Similarity: 106/176 - (60%)
• Gaps: 10/176 - (5%)

  Fly    65 MKHPLEHTWTLWHLEN--DRTKRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKN 127
            :||||...||||:.:.  |:::.|:::|..||||.|||:|:::...:..|.:|.:.:||.||:.:
Yeast    35 VKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRND 99

  Fly   128 IRPMWEDDTNKNGGRWILLLDKASRTYIDKMWHDLLLCMIGECFQHSD-EICGVVINVRNKANKL 191
            :||.|||:.|..||:|...| :.....||::|...||.:|||.....| :|.|||:::|...||.
Yeast   100 VRPEWEDEANAKGGKWSFQL-RGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKF 163

  Fly   192 SLWTKDSRNVEAILSIGRQIKELLHL---GIMEIQYQVHKDAMVNH 234
            :|||| |.:.|.:|.||.:.|::|.|   |  .:::..|..|...|
Yeast   164 ALWTK-SEDKEPLLRIGGKFKQVLKLTDDG--HLEFFPHSSANGRH 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E3	NP_648194.1	IF4E	71..224	CDD:279921	60/158 (38%)
CDC33	NP_014502.1	CDC33	1..213	CDD:227386	67/176 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346524
Domainoid	1	1.000	139	1.000	Domainoid score	I1034
eggNOG	1	0.900	-	-		E1_COG5053
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1143
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54586
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	1	1.000	-	-		otm46506
orthoMCL	1	0.900	-	-		OOG6_100627
Panther	1	1.100	-	-	O	PTHR11960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X406
TreeFam	1	0.960	-	-
	13	12.760