DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF4E3 and Eif4e1b

DIOPT Version :9

Sequence 1:	NP_648194.1	Gene:	eIF4E3 / 38923	FlyBaseID:	FBgn0265089	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	XP_038952114.1	Gene:	Eif4e1b / 686104	RGDID:	1585494	Length:	263	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	85/205 - (41%)
Similarity:	120/205 - (58%)	Gaps:	11/205 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AVYDGLELMSGNEEELQPSLNRVMKNIDYDLAMK-----HPLEHTWTLWHLENDRTKRWAEMLVD 92
            |..:||:   |...:|..||..|.:....:...|     |||:..|.||..:|||::.|.:.|..
  Rat    47 ATAEGLQ---GEARDLPGSLKTVKQKAQREHPTKLPRELHPLQFRWVLWFFKNDRSRAWQDNLQL 108

  Fly    93 VTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKASR-TYID 156
            ||.|:|||||::.|..||..|.|....||.:||:.|:|||||..||.||||:|.|.|..| ..:|
  Rat   109 VTKFDTVEDFWATYRHVKLASKLSCGCDYALFKEGIQPMWEDSRNKRGGRWLLSLAKQQRHMELD 173

  Fly   157 KMWHDLLLCMIGECF-QHSDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKELLHLGIM 220
            ::|.:.|||::||.| ::|.|:||.|:|:|.|.:|::|||.::.|...::.||...||.|.|...
  Rat   174 RLWLETLLCLLGESFEEYSGEVCGAVVNIRTKGDKIALWTSEAENKAGVMHIGHIYKERLGLSTK 238

  Fly   221 E-IQYQVHKD 229
            . |.||.|.|
  Rat   239 TIIGYQAHAD 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E3	NP_648194.1	IF4E	71..224	CDD:279921	69/155 (45%)
Eif4e1b	XP_038952114.1	IF4E	84..243	CDD:396291	71/158 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010