DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF4E3 and eif4e1c

DIOPT Version :9

Sequence 1:	NP_648194.1	Gene:	eIF4E3 / 38923	FlyBaseID:	FBgn0265089	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	XP_005156696.1	Gene:	eif4e1c / 550549	ZFINID:	ZDB-GENE-050417-398	Length:	230	Species:	Danio rerio

Alignment Length:	220	Identity:	88/220 - (40%)
Similarity:	135/220 - (61%)	Gaps:	6/220 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GLAVYDGLEL--MSGNE-EELQPSLNRVMKNIDYDLAMKHPLEHTWTLWHLENDRTKRWAEMLVD 92
            ||..:...:|  |.|.| ||::......:.....:..:||||::.|.||:.:||::|.|.|.|..
Zfish    11 GLGSFRASQLPEMRGTETEEVRSDSPTAVVTTSPEQYIKHPLQNRWALWYFKNDKSKSWTENLRL 75

  Fly    93 VTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKASR-TYID 156
            ::.|:|||||:::|..::.||.|....||.:||..|:||||||.||.||||::.|.|..| ..:|
Zfish    76 ISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLD 140

  Fly   157 KMWHDLLLCMIGECF-QHSDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKELLHLGIM 220
            :.|.:.|||:|||.| :.|:::||.|:|||.|.:|:::||.:.:|.:||::||:|.||.|.|...
Zfish   141 RYWMETLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSK 205

  Fly   221 E-IQYQVHKDAMVNHGPNVNAIYTL 244
            . |.||.|.|.....|.....:|::
Zfish   206 TLIGYQSHDDTSSKSGSTTKNMYSV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E3	NP_648194.1	IF4E	71..224	CDD:279921	70/155 (45%)
eif4e1c	XP_005156696.1	IF4E	54..210	CDD:279921	70/155 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573588
Domainoid	1	1.000	193	1.000	Domainoid score	I3137
eggNOG	1	0.900	-	-		E1_COG5053
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	216	1.000	Inparanoid score	I3585
OMA	1	1.010	-	-		QHG54586
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	1	1.000	-	-		mtm6577
orthoMCL	1	0.900	-	-		OOG6_100627
Panther	1	1.100	-	-	O	PTHR11960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X406
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770