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Protein Alignment eIF4E3 and EIF4E3

DIOPT Version :9

Sequence 1:	NP_648194.1	Gene:	eIF4E3 / 38923	FlyBaseID:	FBgn0265089	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001128123.1	Gene:	EIF4E3 / 317649	HGNCID:	31837	Length:	224	Species:	Homo sapiens

Alignment Length:	205	Identity:	60/205 - (29%)
Similarity:	97/205 - (47%)	Gaps:	36/205 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GLELMSGNEEELQPSLNRVMKNIDYDLAMKHPLEHTWTLW---HLENDRTKRWAEMLVDVTSFNT 98
            ||:.:|.    |||....|            ||..:||.|   .|........|..|..:.:..|
Human    33 GLQQLSA----LQPEPGGV------------PLHSSWTFWLDRSLPGATAAECASNLKKIYTVQT 81

  Fly    99 VEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKASRTYIDKMWHDLL 163
            |:.|:|||..:.|.:.|.:...|.:.:...||:||:::|..||.|.:.:.|.|.:.:   |.:||
Human    82 VQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTV---WKELL 143

  Fly   164 LCMIGE----CFQHSDEICGVVINVRNKANKLSLWTKDSRNVEAIL----SIGRQIKELL-HLGI 219
            |..|||    |....||:.||.::||::.:.:.:|     ||.|.|    ::..:|.||| |:..
Human   144 LATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVW-----NVNASLVGEATVLEKIYELLPHITF 203

  Fly   220 MEIQYQVHKD 229
            ..:.|:.|::
Human   204 KAVFYKPHEE 213

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.