Protein Alignment eIF4E3 and EIF4E

DIOPT Version :10

• Sequence 1: NP_648194.1
• Gene: eIF4E3 / 38923
• FlyBaseID: FBgn0265089
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001124151.1
• Gene: EIF4E / 1977
• HGNCID: 3287
• Length: 248
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 85/227 - (37%)
• Similarity: 121/227 - (53%)
• Gaps: 41/227 - (18%)

  Fly    45 EEELQPSLNRVMKNIDYDLAMKHPLEHTWTLWHLENDRTKRWAEMLVDVTSFNTVEDFFSVYYFV 109
            |||...|...|.....|   :||||::.|.||..:||::|.|...|..::.|:|||||:::|..:
Human    18 EEEKTESNQEVANPEHY---IKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHI 79

  Fly   110 KPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLDKAS-RTYIDKMW----HDL------- 162
            :..|:|....||.:||..|.|||||:.||.||||::.|:|.. |:.:|:.|    .||
Human    80 QLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLV 144

  Fly   163 --------------------LLCMIGECF-QHSDEICGVVINVRNKANKLSLWTKDSRNVEAILS 206
                                |||:|||.| .:||::||.|:|||.|.:|:::||.:..|.||:..
Human   145 SNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTH 209

  Fly   207 IGRQIKELLHLGI---MEIQYQVHKDAMVNHG 235
            |||..||  .||:   :.|.||.|.|.....|
Human   210 IGRVYKE--RLGLPPKIVIGYQSHADTATKSG 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E3	NP_648194.1	IF4E	68..224	CDD:460281	72/191 (38%)
EIF4E	NP_001124151.1	IF4E	38..228	CDD:460281	72/191 (38%)