Protein Alignment KRT86 and ifc-2

DIOPT Version :9

• Sequence 1: XP_005268923.1
• Gene: KRT86 / 3892
• HGNCID: 6463
• Length: 563
• Species: Homo sapiens
• Sequence 2: NP_001362085.1
• Gene: ifc-2 / 180414
• WormBaseID: WBGene00002056
• Length: 1339
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 107/494 - (21%)
• Similarity: 190/494 - (38%)
• Gaps: 104/494 - (21%)

Human   130 GFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 194
            |..:|:....||....|:......|.|.:                  :..::.||.:|..||.|.
 Worm   733 GLASGTYASGFGQLVSGMSSAGAICTTQI------------------RDAREREKREIGLLNDRL 779

Human   195 AAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 259
            |.:|:||||||.||:.|...:...:|......::..||:..|...:...|...|.......::..
 Worm   780 ADYIEKVRFLEAQNRCLSHDIDILRNGFSGGGHVSGLFDAEINQAKHILEQTTAHRSTFERDITG 844

Human   260 VQEVLEGYKKKY------------------------EEEVSL----RATAENEFVALKKDVDCAY 296
            :...:|.::||:                        |.|:||    ....|.:.:.::::.|..|
 Worm   845 LSAEIEVFRKKWLDAVNAVKAHREDHDVDLDRLAKIEAEISLFKRKIRIVEEDVIRIRRENDGIY 909

Human   297 --------------LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLN 347
                          ..|::...||..|:|.|:.|:.  |..:|:.|.     .|.::.|.:.| |
 Worm   910 NEIARIKQLTHNEIALKNERSLNVSDLLQRINLLQT--ENNVRIEQE-----LVFIRRDTTAD-N 966

Human   348 MD-------CIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRM 405
            .|       ..|.:|:|.|:.|..|:|.:.|.|||.:..:::...:|....|  .|||:..:...
 Worm   967 RDYFRHELQAAIRDIRADYEAISIRNRQDIEVWYREQIRKIQDESVRVNPDL--YKEELISIRTT 1029

Human   406 IQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 470
            :..:.:.:...:.:|..||..:...:...||...:  ..|||.:..:...:.....|..:.:::.
 Worm  1030 VTNVRSRLAEVEGRNFFLERLIDDLKNNEEAKFFE--ISLAERDAQIATLRDQCTELSIQMEKLC 1092

Human   471 NSKLGLDIEIATYRRLLEGEEQRLCEGVGSVNVCVSSSRG---GVVCGDLCASTTAPVVS----T 528
            ::::.|..||..||.||.|         .:|....|::.|   |:..|.:...:|. |:|    |
 Worm  1093 DNEISLRAEIERYRILLNG---------ANVTTYTSNTHGSGSGIAVGGVVGGSTR-VISQTTRT 1147

Human   529 RVSSVPSNSNV--------VVGTTNACAPSARVGVCGGS 559
            ..||..|.|||        :.|.....:....:|..|.|
 Worm  1148 HSSSNTSYSNVPASRGGYSISGNVGGISVGGTIGSHGAS 1186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KRT86	XP_005268923.1	Keratin_2_head	<80..179	CDD:292825	7/48 (15%)
		Filament	182..493	CDD:278467	81/359 (23%)
		Prefoldin	302..417	CDD:298833	30/121 (25%)
		RILP-like	<392..>460	CDD:304877	12/67 (18%)
ifc-2	NP_001362085.1	Filament	768..1111	CDD:365827	80/354 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	181	1.000	Domainoid score	I2296
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46601
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920