Protein Alignment Dhps and DHPS

DIOPT Version :10

• Sequence 1: NP_648188.2
• Gene: Dhps / 38917
• FlyBaseID: FBgn0035854
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_001921.1
• Gene: DHPS / 1725
• HGNCID: 2869
• Length: 369
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 227/352 - (64%)
• Similarity: 285/352 - (80%)
• Gaps: 6/352 - (1%)

  Fly     5 PSVAKDAVLKRSEALAENTPQVSGYDFNEGLDYSKLFESYVNTGFQATNLGLAIREINRMLDCRD 69
            |:.|..||||.|..|...:.||.|||||.|::|..|.|::..|||||||.|.|::::|.|::.:.
Human    10 PAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKL 74

  Fly    70 QPLEADQIDSHETDDFIRRR---SKCTVFLGYTSNLVSSGLRETIRFLAEHRMIDCIVTTAGGVE 131
            :||..|: |.|.  |..:.|   :.||:||||||||:|||:|||||:|.:|.|:|.:||||||||
Human    75 EPLSQDE-DQHA--DLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVE 136

  Fly   132 EDFIKCLAPTFMGSFELSGRDLRERGINRIGNLLVPNDNYCKFEDWVMPLLDEMLEEQKSQGTIW 196
            ||.|||||||::|.|.|.|::|||.||||||||||||:||||||||:||:||:|:.||.::|..|
Human   137 EDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKW 201

  Fly   197 SPSKIIHRLGERIGDPSSIYYWAAKNQIPVFCPALTDGSLGDMMYFHSFRQPGLVVDILSDLRRL 261
            :|||:|.|||:.|.:|.|:||||.||.||||.|||||||||||::|||::.||||:||:.|||.:
Human   202 TPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLI 266

  Fly   262 NTMAVKAVNSGMIIVGGGVIKHHICNANLMRNGADYSVFINTASEFDGSDSGARPDEAISWGKIR 326
            ||.|:.|..:||||:||||:||||.|||||||||||:|:||||.||||||||||||||:||||||
Human   267 NTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIR 331

  Fly   327 KDATPVKVYAEASLVFPLIVGETFAKR 353
            .||.||||||:|||||||:|.||||::
Human   332 VDAQPVKVYADASLVFPLLVAETFAQK 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhps	NP_648188.2	DS	39..349	CDD:460382	206/312 (66%)
DHPS	NP_001921.1	DS	44..354	CDD:460382	206/312 (66%)