DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UbcE2M and ube2m

DIOPT Version :9

Sequence 1:	NP_001261567.1	Gene:	UbcE2M / 38916	FlyBaseID:	FBgn0035853	Length:	181	Species:	Drosophila melanogaster
Sequence 2:	NP_988956.1	Gene:	ube2m / 394553	XenbaseID:	XB-GENE-1005525	Length:	183	Species:	Xenopus tropicalis

Alignment Length:	182	Identity:	136/182 - (74%)
Similarity:	154/182 - (84%)	Gaps:	3/182 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKLFTLKQQKKDGEQKG---SQQKKASAAQLRIQKDINELNLPNTCATDFPDPNDLLNFKLIIS 62
            |||||:||||||:.|..|   ...||||||||||||||||||||.||..:|.|.:|||||||:|.
Frog     1 MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCEIEFSDHDDLLNFKLVIC 65

  Fly    63 PDEGFYRDGRFVFNFRVGSNYPHEPPKVKCATQVYHPNIDLDGNVCLNILREDWNPVLNINSIVY 127
            ||||||:.|:|||:|:||..|||:||||||.|.||||||||:||||||||||||.|||.||||:|
Frog    66 PDEGFYKGGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIY 130

  Fly   128 GLQFLFLEPNPEDPLNKEAADVLQTNRRQFENNVKKAMRGGCVGETYFECCL 179
            |||:||||||||||||||||:|||.|||.||.||:::||||.:|.||||.||
Frog   131 GLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UbcE2M	NP_001261567.1	UQ_con	30..165	CDD:395127	104/134 (78%)
ube2m	NP_988956.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		15/26 (58%)
ube2m	NP_988956.1	UQ_con	33..168	CDD:365926	104/134 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	232	1.000	Domainoid score	I2365
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2952
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2753
OMA	1	1.010	-	-		QHG54493
OrthoDB	1	1.010	-	-		D1302735at2759
OrthoFinder	1	1.000	-	-		FOG0003958
OrthoInspector	1	1.000	-	-		otm48577
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4810
SonicParanoid	1	1.000	-	-		X2724
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110