DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and AgaP_AGAP005908

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_001688751.1	Gene:	AgaP_AGAP005908 / 5667045	VectorBaseID:	AGAP005908	Length:	403	Species:	Anopheles gambiae

Alignment Length:	389	Identity:	117/389 - (30%)
Similarity:	187/389 - (48%)	Gaps:	37/389 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 YPDRQREAKRTSAGATPQQVSSPAVKYPQSRGMPKDYYYKVLGVNRHATIQQIRSAFYALAKRYH 128
            :|...:.|.:..:..:..:.||.||..|:.. .||| :|.||||:|.|:...|:.|:|.|||::|
Mosquito    25 FPSGDKSADKQPSSKSTGKSSSKAVPPPKVT-PPKD-FYAVLGVSRTASFNDIKKAYYELAKQFH 87

  Fly   129 PDSTHSEQKL------------KHFQELSNAYNILTDETKR-------LEYDQLGGIKDERAFLE 174
            ||...::|..            |.|.:::.||..|..|.|.       |.......::.:...|.
Mosquito    88 PDRRTAQQNSNSTAKESTAAMEKKFSQITEAYEALLVEVKHRTESVVDLNPSLYRDLQKKHMLLP 152

  Fly   175 QAGNPLNVGLEEAKKFDSDKTTNDEINKLKSNEFDLPLDFLEATVGCKKRIELRYLRKCETCKGK 239
            :.|...|.         :..||  .||:|...:..|.|.|.|:..|..:.:.|....||:.|...
Mosquito   153 KNGQSGNT---------APPTT--LINELNYEDVVLTLTFKESIEGTVRELTLPIGVKCDRCSYT 206

  Fly   240 SQLMAHRDVGKEPCRRCNGTGKVMTKTPTFSSVNTCTQCKGKRFT-NRNDCETCSNRGFVVSNVD 303
            ....|....|.  |..|:||||....|.:...:..|..|.|.:.| ::..|..|..:|.|:....
Mosquito   207 GTQSALDPEGL--CSICHGTGKQEFHTESGKLLMPCKFCNGSKHTPHKLTCPKCHGKGIVMKQHP 269

  Fly   304 VMVSVPSGSRDGDVVNIINPETKQQVTYRLSVPSSDYFRRVGNDILTDKHLNISEAILGGSFQIR 368
            :.||:|..|:..|.:.:..|..::|:|..|.|....:|||||.:|.:.:.:.:.:||.||...||
Mosquito   270 LTVSIPKASQHKDRLKVRIPGLQRQLTVILHVQDQGHFRRVGLNIYSTEEITMLKAIRGGDLSIR 334

  Fly   369 GLYESVELRVEPGTQSHTQVVLNGKGVRS--REGVGNHIVTLKVRIPRNLSVKQRQLVLALSQA 430
            |:.....:.:|||||..|::.:.|||:|.  |:.||:||:||::|:||.|:.:|.||:....:|
Mosquito   335 GINGIFNVYLEPGTQFGTELRIPGKGLRDELRQDVGDHILTLQIRLPRTLTPRQLQLLEEFERA 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	107/352 (30%)
		DnaJ	101..161	CDD:278647	25/78 (32%)
		DnaJ_zf	233..296	CDD:199908	17/63 (27%)
		DnaJ_C	298..416	CDD:199909	44/119 (37%)
AgaP_AGAP005908	XP_001688751.1	DnaJ	59..398	CDD:223560	107/352 (30%)
		DnaJ	59..122	CDD:278647	22/63 (35%)
		DnaJ_zf	200..262	CDD:304418	17/63 (27%)
		DnaJ_C	263..384	CDD:199909	44/120 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0715
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D894595at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890