DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and LOC554962

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001116708.1	Gene:	LOC554962 / 554962	-ID:	-	Length:	474	Species:	Danio rerio

Alignment Length:	474	Identity:	140/474 - (29%)
Similarity:	222/474 - (46%)	Gaps:	73/474 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSTLISGAATDCCRKTSHCLELDRAPAVAACWICMRMISQYQFRTTKPAYYPDRQREAKRTSAGA 78
            ||....|..::|.     .|:..|...|.|..||.           ..:|..::.....|...|.
Zfish     9 LSGAFPGLHSNCA-----LLKSSRNGDVTALRICW-----------SRSYVTEKSLSCWRHRGGV 57

  Fly    79 TPQQVSSPAVK---------YPQSRGMPKDYYYKVLGVNRHATIQQIRSAFYALAKRYHPDSTHS 134
            |.:::  ||::         :..|.|..:..:|:||||.|.|:.::|:.|:|.|||:||||:...
Zfish    58 TLRRI--PALRPHSVFSSHFFHTSSGFRQQDFYEVLGVPRTASQKEIKKAYYQLAKKYHPDTNPD 120

  Fly   135 EQKLKH-FQELSNAYNILTDETKRLEYDQLG-------GIKDERAFLEQAGNPLNVGLEEA---- 187
            :...|. |.:|:.||..|:||.||.:||..|       |...::.:...|    ||..||.
Zfish   121 DPDAKEKFAKLAEAYETLSDELKRKQYDTYGSAGPSASGTGQQQYWRGSA----NVDPEELFRKI 181

  Fly   188 -KKFDSDKTTNDEINKL--KSNEFDLPLDFLEATVGCKKRIELRYLRKCETCKGKSQLMAHRDVG 249
             .:|...:...| ||.:  ::.||.:.|.|::|..|..|.|.:.....|..|.||:
Zfish   182 FGEFAGGRGFGD-INSMFDQTPEFVMELSFMQAAKGVNKEITVNIDDDCPRCDGKA--------- 236

  Fly   250 KEP------CRRCNGTGKVMTKTPTFSSVNTCTQCKGKRFTNRNDCETCSNRGFVVSNVDVMVSV 308
            .||      |..|||||.....|..|...:.|.:|.|:.|.....|..|...|.......|||.|
Zfish   237 FEPGTKVSHCHYCNGTGMESINTGPFMMRSACRRCSGRGFIIITPCIMCRGSGQTKQKQTVMVPV 301

  Fly   309 PSGSRDGDVVNIINPETKQQVTYRLSVPSSDYFRRVGNDILTDKHLNISEAILGGSFQIRGLYES 373
            |:|..||..|.:...:....:|:|  |..|..|||.|.||.:|..::|::|||||:.:.:|||.:
Zfish   302 PAGIADGQTVKVPVGKKYMYITFR--VQKSPVFRRDGADIHSDVMISIAQAILGGTARAQGLYST 364

  Fly   374 VELRVEPGTQSHTQVVLNGKGV--RSREGVGNHIVTLKVRIPRNLSVKQRQLVLALSQAEDP--- 433
            :::.:.||.|:..::.|.|||:  .:..|.|:|.|.:|::||:.|:.:|:.|:|:.::.|:.
Zfish   365 IDIAIPPGIQTDHKIKLEGKGIPRMNSFGYGDHYVYIKIKIPKKLTRRQKMLLLSFAEDEEDVEG 429

  Fly   434 ----VFEPKTKSTEAGNLS 448
                |.:|....::||..|
Zfish   430 TVNGVTKPDPGRSQAGQTS 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	116/352 (33%)
		DnaJ	101..161	CDD:278647	27/60 (45%)
		DnaJ_zf	233..296	CDD:199908	20/68 (29%)
		DnaJ_C	298..416	CDD:199909	43/119 (36%)
LOC554962	NP_001116708.1	DnaJ	85..428	CDD:223560	117/358 (33%)
		DnaJ	86..148	CDD:278647	27/61 (44%)
		DnaJ_C	203..409	CDD:199909	72/216 (33%)
		DnaJ_zf	229..289	CDD:199908	20/68 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020