DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and dnaja3b

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_958499.1	Gene:	dnaja3b / 394242	ZFINID:	ZDB-GENE-040115-3	Length:	474	Species:	Danio rerio

Alignment Length:	472	Identity:	139/472 - (29%)
Similarity:	223/472 - (47%)	Gaps:	69/472 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSTLISGAATDCCRKTSHCLELDRAPAVAACWICMRMISQYQFRTTKPAYYPDRQREAKRTSAGA 78
            ||....|..::|.     .|:..|...|.|..||.           ..:|..::.....|...|.
Zfish     9 LSGAFPGLHSNCA-----LLKSSRNGDVTALRICW-----------SRSYVTEKSLSCWRHRGGV 57

  Fly    79 TPQQVSSPAVK---------YPQSRGMPKDYYYKVLGVNRHATIQQIRSAFYALAKRYHPDSTHS 134
            |.:::  ||::         :..|.|..:..:|:||||.|.|:.::|:.|:|.|||:||||:...
Zfish    58 TLRRI--PALRPHSVFSSHFFHTSSGFRQQDFYEVLGVPRTASQKEIKKAYYQLAKKYHPDTNPD 120

  Fly   135 EQKLKH-FQELSNAYNILTDETKRLEYDQLG-------GIKDERAFLEQAGNPLNVGLEEA---- 187
            :...|. |.:|:.||..|:||.||.:||..|       |...::.:...|    ||..||.
Zfish   121 DPDAKEKFAKLAEAYETLSDELKRKQYDTYGSAGPSASGTGQQQYWRGSA----NVDPEELFRKI 181

  Fly   188 -KKFDSDKTTNDEINKL--KSNEFDLPLDFLEATVGCKKRIELRYLRKCETCKGKS----QLMAH 245
             .:|...:...| ||.:  ::.||.:.|.|::|..|..|.|.:.....|..|.||:    ..::|
Zfish   182 FGEFAGGRGFGD-INSMFDQAPEFVMELSFMQAAKGVNKEITVNIDDDCPRCDGKAFEPGTKVSH 245

  Fly   246 RDVGKEPCRRCNGTGKVMTKTPTFSSVNTCTQCKGKRFTNRNDCETCSNRGFVVSNVDVMVSVPS 310
                   |..|||||.....|..|...:.|.:|.|:.|.....|..|...|.......|||.||:
Zfish   246 -------CHYCNGTGMESINTGPFMMRSACRRCSGRGFIIITPCIMCRGSGQTKQKQTVMVPVPA 303

  Fly   311 GSRDGDVVNIINPETKQQVTYRLSVPSSDYFRRVGNDILTDKHLNISEAILGGSFQIRGLYESVE 375
            |..||..|.:...:....:|:|  |..|..|||.|.||.:|..::|::|||||:.:.:|||.:::
Zfish   304 GIADGQTVKVPVGKKHMYITFR--VQKSPVFRRDGADIHSDVLISIAQAILGGTARAQGLYSTID 366

  Fly   376 LRVEPGTQSHTQVVLNGKGV--RSREGVGNHIVTLKVRIPRNLSVKQRQLVLALSQAEDP----- 433
            :.:.||.|:..::.|.|||:  .:..|.|:|.|.:|::||:.|:.:|:.|:|:.::.|:.
Zfish   367 IAIPPGIQTDHKIKLEGKGIPRMNSFGYGDHYVYIKIKIPKKLTRRQKMLLLSFAEDEEDVEGTV 431

  Fly   434 --VFEPKTKSTEAGNLS 448
              |.:|....::||..|
Zfish   432 NGVTKPAPGRSQAGQTS 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	115/350 (33%)
		DnaJ	101..161	CDD:278647	27/60 (45%)
		DnaJ_zf	233..296	CDD:199908	19/66 (29%)
		DnaJ_C	298..416	CDD:199909	43/119 (36%)
dnaja3b	NP_958499.1	DnaJ	85..428	CDD:223560	116/356 (33%)
		DnaJ	86..148	CDD:278647	27/61 (44%)
		DnaJ_C	203..409	CDD:199909	71/214 (33%)
		DnaJ_zf	229..289	CDD:199908	19/66 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D436402at33208
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030