DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and Dnaja3

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001033684.2	Gene:	Dnaja3 / 360481	RGDID:	1306527	Length:	480	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	120/362 - (33%)
Similarity:	185/362 - (51%)	Gaps:	33/362 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 SRGMPKDYYYKVLGVNRHATIQQIRSAFYALAKRYHPDSTHSEQKLKH-FQELSNAYNILTDETK 156
            |..:.||.||::|||.|:|:.:.|:.|:|.|||:||||:...:.|.|. |.:|:.||.:|:||.|
  Rat    86 SASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVK 150

  Fly   157 RLEYDQLG--GIKDERAFLEQA---GNPLNVGLEEAKKFDSDKTTNDEINKLKSNEFDLP----- 211
            |.:||..|  |.....:...|.   |.| :|..||..:....:.::......: |.||.|
  Rat   151 RKQYDAYGSAGFDPGASSSGQGYWRGGP-SVDPEELFRKIFGEFSSSPFGDFQ-NVFDQPQEYIM 213

  Fly   212 -LDFLEATVGCKKRIELRYLRKCETCKGKSQLMAHRDVGKEP------CRRCNGTGKVMTKTPTF 269
             |.|.:|..|..|...:..:..||.|.||         |.||      |..|:|:|.....|..|
  Rat   214 ELTFNQAAKGVNKEFTVNIMDTCERCDGK---------GNEPGTKVQHCHYCSGSGMETINTGPF 269

  Fly   270 SSVNTCTQCKGKRFTNRNDCETCSNRGFVVSNVDVMVSVPSGSRDGDVVNIINPETKQQVTYRLS 334
            ...:||.:|.|:.....|.|..|...|.......|.|.||:|..||..|.:  |..|:::.....
  Rat   270 VMRSTCRRCGGRGSIITNPCVVCRGAGQAKQKKRVTVPVPAGVEDGQTVRM--PVGKREIFVTFR 332

  Fly   335 VPSSDYFRRVGNDILTDKHLNISEAILGGSFQIRGLYESVELRVEPGTQSHTQVVLNGKGVR--S 397
            |..|..|||.|.||.:|..::|::|||||:.:.:||||::.:.:..|.|:..::.|.|||:.  :
  Rat   333 VQKSPVFRRDGADIHSDLFISIAQAILGGTAKAQGLYETINVTIPAGIQTDQKIRLTGKGIPRIN 397

  Fly   398 REGVGNHIVTLKVRIPRNLSVKQRQLVLALSQAEDPV 434
            ..|.|:|.:.:|:|:|:.||.:|:.|:|:.::.|..|
  Rat   398 SYGYGDHYIHIKIRVPKRLSSRQQNLILSYAEDETDV 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	115/349 (33%)
		DnaJ	101..161	CDD:278647	28/60 (47%)
		DnaJ_zf	233..296	CDD:199908	21/68 (31%)
		DnaJ_C	298..416	CDD:199909	41/119 (34%)
Dnaja3	NP_001033684.2	DnaJ	90..480	CDD:223560	119/358 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0715
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D436402at33208
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890