DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and mdj1

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_587824.1	Gene:	mdj1 / 2539501	PomBaseID:	SPCC4G3.14	Length:	528	Species:	Schizosaccharomyces pombe

Alignment Length:	431	Identity:	118/431 - (27%)
Similarity:	190/431 - (44%)	Gaps:	61/431 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 QREAKRT-SAGATPQQVSSPAVKYPQSRGM-----PKDYYYKVLGVNRHATIQQIRSAFYALAKR 126
            ||.|||. |..|..:..|..|..:..:|.:     |    ||.|||::.|:..:|:||:|.|||:
pombe    52 QRNAKREFSRCAALKNFSYHARCFHATRAVWEMTDP----YKTLGVSKSASASEIKSAYYKLAKQ 112

  Fly   127 YHPDSTHSEQKLKHFQELSNAYNILTDETKRLEYDQLG-------------------GIKDERAF 172
            ||||:...:.....|.|:..||.:|.|..|:..:|..|                   |.....:|
pombe   113 YHPDANPDKAAQDKFVEIKQAYEVLQDPKKKKAFDTYGAGAFKNGEFTGGDFEGFQNGFAGASSF 177

  Fly   173 LEQAGNPLNVGLEEAKKFDS-----DKTTNDEINKLKSNEFDLPLDFLEATVGCKKRIELRYLRK 232
              .:|.| ....|:...|.|     .:.|:.::...:..|..:.:||:||..|.||.:.......
pombe   178 --SSGFP-GFNFEDLFGFSSRGPQARRNTSFDVFVGEDIEASITIDFMEAVRGAKKDLSYSVSST 239

  Fly   233 CETCKGKS-QLMAHRDVGKEPCRRCNGTG-KVMTKTPTFSSVNTCTQCKGKRFT--NRNDCETCS 293
            |.:|.|.. |..:|    |..|..|.||| ::....|:|....||..|.|...|  ..:.|.:|.
pombe   240 CSSCHGSGLQPGSH----KSTCFACKGTGQRLHFIPPSFHMQTTCDSCGGTGTTIPPNSACRSCM 300

  Fly   294 NRGFVVSNVDVMVSVPSGSRDGDVVNII-----------NPETKQQ---VTYRLSVPSSDYFRRV 344
            ..|.|.....|.:.:|.|..|..|:.::           .|..|.:   :...:.|....:|.|.
pombe   301 GSGTVRERKTVSIDIPPGIDDNTVLRVMGAGNDASTAKGGPNAKSRPGDLFATIHVRKHPFFVRE 365

  Fly   345 GNDILTDKHLNISEAILGGSFQIRGLYESVELRVEPGTQSHTQVVLNGKGVR--SREGVGNHIVT 407
            |.::..:..:.::.|.|||:.::..|..:|:|||.|||.:..::.:.|||:|  :....||..|.
pombe   366 GTNVTYNAKIPMTTAALGGTLRVPTLTGNVDLRVSPGTSTGDRITMAGKGIRKVNTSRYGNFYVN 430

  Fly   408 LKVRIPRNLSVKQRQLVLALSQAEDPVFEPKTKSTEAGNLS 448
            .:|.||:.||..:|.|:..|:.|.:.....:|:|:.:|..|
pombe   431 FEVTIPKILSPHERSLLEQLADALNDSTARRTQSSPSGTNS 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	102/373 (27%)
		DnaJ	101..161	CDD:278647	24/59 (41%)
		DnaJ_zf	233..296	CDD:199908	20/66 (30%)
		DnaJ_C	298..416	CDD:199909	34/133 (26%)
mdj1	NP_587824.1	DnaJ	82..457	CDD:223560	104/385 (27%)
		DnaJ	86..147	CDD:278647	25/64 (39%)
		DnaJ_zf	243..303	CDD:199908	19/63 (30%)
		DnaJ_C	304..439	CDD:199909	34/134 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0715
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870