DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and dnj-10

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_498902.1	Gene:	dnj-10 / 176211	WormBaseID:	WBGene00001028	Length:	456	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	116/383 - (30%)
Similarity:	183/383 - (47%)	Gaps:	48/383 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 QVSSP---AVKYPQ---SRGMPKDYYYKVLGVNRHATIQQIRSAFYALAKRYHPDSTHSEQKLKH 140
            |||:|   ..|..|   :..:.|:.|||.|||::.:..:.|:.|::.|||:||||...:::....
Worm    20 QVSTPTTSTTKLAQLHTTHALSKEDYYKTLGVDKKSDAKAIKKAYFQLAKKYHPDVNKTKEAQTK 84

  Fly   141 FQELSNAYNILTDETKRLEYDQLGGIKDERAFLEQAGNPL-------------NVGLEEAKK--- 189
            |||:|.||.:|:|:|||.|||..|          ..|.|.             ||.:.|..:
Worm    85 FQEISEAYEVLSDDTKRQEYDAYG----------SGGGPAGGRGGAGGFHHHGNVDVNEIFRRAF 139

  Fly   190 --------FDSDKTTNDEINKLKSNEFDLPLDFLEATVGCKKRIELRYLRKCETCKGKSQLMAHR 246
                    |:.|...........:.|..:.:.|.||..|..|.:.:..:..|..|.|......|:
Worm   140 GGGGGMGGFNFDNFAQSAFGHSAAQEMVMDISFEEAVRGATKNVSVNVVEDCLKCHGTQVEPGHK 204

  Fly   247 DVGKEPCRRCNGTGKVMTKTP-TFSSVNTCTQCKGKRFTNRNDCETCSNRGFVVSNVDVMVSVPS 310
               |..|..|||||.|..:.. .|....||.:|:|....|:|.|:.|...|..|....|..:||:
Worm   205 ---KTSCPYCNGTGAVSQRLQGGFFYQTTCNRCRGSGHYNKNPCQECEGEGQTVQRRQVSFNVPA 266

  Fly   311 GSRDGDVVNIINPETKQQVTYRLSVPSSDYFRRVGNDILTDKHLNISEAILGGSFQIRGLYESVE 375
            |:.:||.:..  ...|.|:..|.:|..|..|||..:||..|..:::::|:|||:.::.|:.....
Worm   267 GTNNGDSLKF--QVGKNQLFVRFNVAPSLKFRREKDDIHCDVDISLAQAVLGGTVKVPGINGDTY 329

  Fly   376 LRVEPGTQSHTQVVLNGKGVRSREGVGN--HIVTLKVRIPRNLSVKQRQLVLALSQAE 431
            :.:..||.|||::.|.||||:.....||  ..:.:||.:|:.|:.:|:|::||.:..|
Worm   330 VHIPAGTGSHTKMRLTGKGVKRLHSYGNGDQYMHIKVTVPKYLTAEQKQIMLAWAATE 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	108/356 (30%)
		DnaJ	101..161	CDD:278647	27/59 (46%)
		DnaJ_zf	233..296	CDD:199908	21/63 (33%)
		DnaJ_C	298..416	CDD:199909	38/119 (32%)
dnj-10	NP_498902.1	DnaJ	41..387	CDD:223560	109/360 (30%)
		DnaJ	44..105	CDD:278647	27/60 (45%)
		DnaJ_C	165..372	CDD:199909	66/211 (31%)
		DnaJ_zf	191..252	CDD:199908	21/63 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1730
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D436402at33208
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.980