DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7387 and AgaP_AGAP007565

DIOPT Version :9

Sequence 1:	NP_648186.3	Gene:	CG7387 / 38915	FlyBaseID:	FBgn0035852	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_308308.4	Gene:	AgaP_AGAP007565 / 1269663	VectorBaseID:	AGAP007565	Length:	574	Species:	Anopheles gambiae

Alignment Length:	437	Identity:	137/437 - (31%)
Similarity:	209/437 - (47%)	Gaps:	72/437 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FRLKLFRSPG--DVLSTLISGAAT-DCCRKTSHCLELDRAPAVAACWICMRMISQYQF-----RT 58
            |.|...|.||  ..:...:.|.|| ..|    ||:..:::|           |.::.|     .|
Mosquito    15 FGLLNARFPGRSAPIGVAVPGVATVGAC----HCIITNQSP-----------IRRHLFTPAITST 64

  Fly    59 TKPAYY----PDRQREAKRTSAGATPQQVSSPAVKYPQSRGMPKDYYYKVLGVNRHATIQQIRSA 119
            |..|..    |.|.:....:|..:|.|...|    :..|..:.|..||..|||.::|:.::|:.|
Mosquito    65 TAAAAASSSGPSRLQRPSPSSRCSTLQSTRS----FYTSNILHKSDYYSTLGVTKNASPKEIKKA 125

  Fly   120 FYALAKRYHPDSTHSEQKL-KHFQELSNAYNILTDETKRLEYDQLGGIKDERAFLEQAGNPLNVG 183
            :|.|||:||||:...:... |.|||:|.||.:|:|||||.|||..|...::   :.:||.....|
Mosquito   126 YYQLAKKYHPDTNKDDPNAGKKFQEVSEAYEVLSDETKRREYDTYGQTSEQ---MGRAGGGPGPG 187

  Fly   184 L------------------EEAKKFDSD---KTTNDEINKLK-----SNEFDLPLDFLEATVGCK 222
            .                  |..:|...|   :|..|:.:..|     :.|..:.|.|.:|..|..
Mosquito   188 AGPQGFSQNWQFRSTIDPEELFRKIFGDGGFQTGFDDYSDSKFGFGGAQEVMMNLTFAQAARGVN 252

  Fly   223 KRIELRYLRKCETCKGKSQLMAHRDVGKEP--CRRCNGTGKVMTKTPTFSSVNTCTQCKGKRFTN 285
            |.|::..:..|..|.|     :..:.|.:|  |:.|||||.....|..|...:||..|:|.|...
Mosquito   253 KDIDVNVVDTCPKCTG-----SRCEPGTKPGKCQYCNGTGMETISTGPFVMRSTCRYCQGTRMYI 312

  Fly   286 RNDCETCSNRGFVVSNVDVMVSVPSGSRDGDVVNIINPETKQ-QVTYRLSVPSSDYFRRVGNDIL 349
            :..|..|..:|..|....|.|.||:|..||..|. :|..:|: .:|:|  |..|.||||.|.|:.
Mosquito   313 KYPCLECGGKGQTVQRKRVTVPVPAGIEDGQTVR-MNVGSKEIFITFR--VEKSRYFRRDGADVH 374

  Fly   350 TDKHLNISEAILGGSFQIRGLYESVELRVEPGTQSHTQVVLNGKGVR 396
            ||.::::|:|||||:.:::|:||...:::.|||.|||::.|.|||::
Mosquito   375 TDANISLSQAILGGTIRVQGVYEDQTIQITPGTSSHTRITLTGKGLK 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7387	NP_648186.3	DnaJ_bact	101..431	CDD:274090	112/326 (34%)
		DnaJ	101..161	CDD:278647	30/60 (50%)
		DnaJ_zf	233..296	CDD:199908	20/64 (31%)
		DnaJ_C	298..416	CDD:199909	42/100 (42%)
AgaP_AGAP007565	XP_308308.4	PRK14296	102..436	CDD:237666	113/331 (34%)
		DnaJ	106..168	CDD:278647	30/61 (49%)
		DnaJ_CXXCXGXG	263..323	CDD:279074	20/64 (31%)
		DnaJ_C	324..422	CDD:199909	42/101 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D436402at33208
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44145
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030