DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7387 and Dnajc2

DIOPT Version :9

Sequence 1:NP_648186.3 Gene:CG7387 / 38915 FlyBaseID:FBgn0035852 Length:449 Species:Drosophila melanogaster
Sequence 2:NP_446228.2 Gene:Dnajc2 / 116456 RGDID:620524 Length:621 Species:Rattus norvegicus


Alignment Length:429 Identity:84/429 - (19%)
Similarity:146/429 - (34%) Gaps:129/429 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 KYPQSRGM-PKDY----YYKVLG---VNRHATIQQIRSAFYALAKRYHPDSTHS------EQKLK 139
            ::|..:.: |||:    :|.|||   |...||.:||::|...:..::|||...:      |....
  Rat    72 EFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKTMVLKHHPDKRKAAGEPIKEGDND 136

  Fly   140 HFQELSNAYNILTDETKRLEYDQLGGIKD----------ERAFLEQAGNP--------------- 179
            :|..::.||.:|:|..||..::.:....|          |..|  |..:|               
  Rat   137 YFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKENFF--QVFSPVFERNSRWSNKKNVP 199

  Fly   180 ----LNVGLEEAK-------KFDSDKTTN--DEINKLKSNEFDLPLDFLE----ATVGCKKRIEL 227
                :|...|:..       .|||.:..:  ||..|.|:...| ...::|    ||...:|:.|:
  Rat   200 KLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRD-ERKWIEKQNRATRAQRKKEEM 263

  Fly   228 RYLR----KCETC---------KGKSQLMAHRDVGKEPCRRCNGTGKVMTKTPTFSSVNTCTQ-- 277
            ..:|    ...:|         :||::..|.:. .|...||.....|...:.....:|....:  
  Rat   264 NRIRTLVDNAYSCDPRIKKFKEEGKAKKEAEKR-AKAEARRKEQEAKEKQRQAELEAVRLAKEKE 327

  Fly   278 ---------------------CKGKRFTNRNDCETCSNRGFVVSNVDVMVSVPSGSRDGDVVNII 321
                                 .|.:|...||.|:..::               ....:.|.|.::
  Rat   328 EEEVRQQALLAKKEKEIQKKAIKKERQKLRNSCKNWNH---------------FSDNEADRVKMM 377

  Fly   322 NPETKQQVTYRLSVPSSDYFRRVGNDILTDKHLNISEAILGGSFQIRGLYESVELRVEPGTQSHT 386
              |..:::..||.:.|....    |:||......:.:|.|  ..||..:.|.:....|.......
  Rat   378 --EEVEKLCDRLELASLQCL----NEILASSTREVGKAAL--EKQIEEVNELMRKEKEEADARMR 434

  Fly   387 QVVLNGKGVRSREGVGNHIVTLKVRIPRNLSVKQRQLVL 425
            |...|.:....|.|.|:          :|.|....||::
  Rat   435 QASKNAEKSTGRSGSGS----------KNWSEDDLQLLI 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7387NP_648186.3 DnaJ_bact 101..431 CDD:274090 80/412 (19%)
DnaJ 101..161 CDD:278647 21/68 (31%)
DnaJ_zf 233..296 CDD:199908 14/94 (15%)
DnaJ_C 298..416 CDD:199909 20/117 (17%)
Dnajc2NP_446228.2 DnaJ 88..158 CDD:278647 21/69 (30%)
ZRF1-UBD 160..250 16/92 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 287..312 7/25 (28%)
GBP_C <288..353 CDD:303769 8/65 (12%)
RAC_head 349..420 CDD:293322 18/93 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 426..453 6/36 (17%)
SANT 452..508 CDD:197842 4/12 (33%)
SANT 453..506 CDD:238096 4/11 (36%)
SANT 553..602 CDD:197842
SANT 553..600 CDD:238096
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.