| Sequence 1: | NP_001261565.1 | Gene: | Atg18a / 38913 | FlyBaseID: | FBgn0035850 | Length: | 447 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060453.3 | Gene: | WIPI1 / 55062 | HGNCID: | 25471 | Length: | 446 | Species: | Homo sapiens |
| Alignment Length: | 403 | Identity: | 190/403 - (47%) |
|---|---|---|---|
| Similarity: | 268/403 - (66%) | Gaps: | 24/403 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 NFNQNITSLAVATSGGYSLYSLGSVDSTLDKIYHTKS-DELFLIERLFESSLVAIVSQRAPRKLK 81
Fly 82 VCHFKKQSEICNYSYANTILAVKLNRERLIVCLEESLYIHNIQDMKVVHTIRDTPCNPQGLCALS 146
Fly 147 SSSEHCYLAYPGSVTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPSGTEIATASERGTVIRVF 211
Fly 212 SSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTETVHIFRLDRSATETAEGHGSKQSSD 276
Fly 277 DWMGYSFFRFLSKTVTSYLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIASQDG 341
Fly 342 YLYVYSIPTVEGAECQLIKRHDL----RLEDHYAMDIKVDSPQTLGLNSGVSIGGAAGVPPSSAS 402
Fly 403 AAGAGTGGSGGDG 415 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Atg18a | NP_001261565.1 | WD40 | <15..278 | CDD:225201 | 134/260 (52%) |
| WD40 | 23..269 | CDD:295369 | 131/246 (53%) | ||
| WD40 repeat | 143..180 | CDD:293791 | 16/36 (44%) | ||
| WD40 repeat | 186..231 | CDD:293791 | 27/44 (61%) | ||
| WD40 repeat | 232..258 | CDD:293791 | 16/25 (64%) | ||
| WIPI1 | NP_060453.3 | WD 1 | 3..42 | 11/20 (55%) | |
| WD 2 | 47..88 | 15/41 (37%) | |||
| WD40 | <77..>262 | CDD:225201 | 105/184 (57%) | ||
| WD40 | <88..262 | CDD:295369 | 101/173 (58%) | ||
| WD 3 | 92..126 | 23/33 (70%) | |||
| WD 4 | 131..173 | 21/41 (51%) | |||
| Nuclear receptor interaction | 131..136 | 1/4 (25%) | |||
| WD40 repeat | 145..184 | CDD:293791 | 18/38 (47%) | ||
| WD 5 | 177..216 | 20/38 (53%) | |||
| WD40 repeat | 189..226 | CDD:293791 | 22/36 (61%) | ||
| WD 6 | 222..261 | 24/38 (63%) | |||
| WD40 repeat | 236..268 | CDD:293791 | 16/31 (52%) | ||
| WD40 repeat | 274..312 | CDD:293791 | 18/39 (46%) | ||
| WD 7 | 304..343 | 19/38 (50%) | |||
| WD40 repeat | 320..358 | CDD:293791 | 19/37 (51%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 386..406 | 7/19 (37%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141945 | |
| Domainoid | 1 | 1.000 | 415 | 1.000 | Domainoid score | I667 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2110 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 415 | 1.000 | Inparanoid score | I1840 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54442 | |
| OrthoDB | 1 | 1.010 | - | - | D1216824at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001466 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41432 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11227 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R106 |
| SonicParanoid | 1 | 1.000 | - | - | X1186 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.900 | |||||