Protein Alignment Atg18a and epg-6

DIOPT Version :9

• Sequence 1: NP_001261565.1
• Gene: Atg18a / 38913
• FlyBaseID: FBgn0035850
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_871659.1
• Gene: epg-6 / 189705
• WormBaseID: WBGene00012641
• Length: 388
• Species: Caenorhabditis elegans
• Alignment Length: 274
• Identity: 79/274 - (28%)
• Similarity: 134/274 - (48%)
• Gaps: 32/274 - (11%)

  Fly    24 TSLAVATSGGYSLYSLGSVDSTLDKIYHTKSDELFLIERLFESSLVAIVSQRAPRK--------L 80
            ::.|:|...|:.:|.|..:...:.|.|..|...:.|:::...|..:..||..|..:        .
 Worm    46 SAFAIADKDGFKMYQLNPLHFRMYKDYVIKVGPVRLVKQDGNSRRIIYVSALAGGRFAQNNLMIF 110

  Fly    81 KVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEESLYIHNI-QDMKVVHTIRDTPCNPQGLCA 144
            .|...::..||...|....|..:.::..||:......:::... .|:|.:.: .|...||:|:.|
 Worm   111 DVARNEEYFEITTPSRYGPITNIHVSPNRLVALNPNRMFVWTYPDDIKQIRS-EDIRSNPKGISA 174

  Fly   145 LS--SSSEHCYLAYPGSVTAGEVQIFDAINLHAKT--------MIPAHDTPLAALAFSPSGTEIA 199
            :|  .::..|||||||..| |.|||   ::|:|.|        :|.||.|.:|.:|.:..||.:|
 Worm   175 MSYDPTTAACYLAYPGFKT-GSVQI---MHLNALTARESKSPIVIEAHLTDIAQVALNCQGTLVA 235

  Fly   200 TASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTETVHIFRL------ 258
            |.|.:|||||||.::....|:|||||..: ..:..::||.|:.||..:|:..|:|:|.:
 Worm   236 TGSTKGTVIRVFDARTKGPLYELRRGTVQ-AHLQCMAFSPCSSYLAVASDKGTLHMFGIRDAEPQ 299

  Fly   259 -DRSATETAEGHGS 271
             .::..|.:.|..|
 Worm   300 KKKNVLERSRGSSS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg18a	NP_001261565.1	WD40	<15..278	CDD:225201	79/274 (29%)
		WD40	23..269	CDD:295369	77/270 (29%)
		WD40 repeat	143..180	CDD:293791	17/46 (37%)
		WD40 repeat	186..231	CDD:293791	20/44 (45%)
		WD40 repeat	232..258	CDD:293791	9/25 (36%)
epg-6	NP_871659.1	WD40	9..>320	CDD:225201	79/274 (29%)
		WD40 repeat	80..124	CDD:293791	8/43 (19%)
		WD40 repeat	129..170	CDD:293791	7/41 (17%)
		WD40 repeat	173..216	CDD:293791	17/46 (37%)
		WD40 repeat	222..259	CDD:293791	16/36 (44%)
		WD40 repeat	267..306	CDD:293791	9/38 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54442
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R106
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950