Protein Alignment ERR and nhr-108

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_506987.1
• Gene: nhr-108 / 180065
• WormBaseID: WBGene00003698
• Length: 338
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 87/380 - (22%)
• Similarity: 139/380 - (36%)
• Gaps: 116/380 - (30%)

  Fly   127 CLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNECEINKRRRKACQACRFQKCLLMG 191
            |:|||:::....:|..||.||..||:|.|..........|..|::.|..||.||:|||||||.:|
 Worm    10 CMVCGEISYSIRFGAVSCRACAEFFRRKIVSKARIPKRCNGACDLGKYHRKTCQSCRFQKCLKIG 74

  Fly   192 MLKEGVRLDRVRGGRQKYRRNPV---SNSYQT----MQLLYQSNTTSLCDV-----KILEVLNSY 244
            ||::.|.           .|.||   |.:.||    ::..|.....|..:|     ||.:..|..
 Worm    75 MLEKVVA-----------SRTPVNRRSENNQTILSGLEKAYDKLENSRDNVFDRKNKIPKYCNHQ 128

  Fly   245 EPDALSVQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNN--NDPNEILSVLSD 307
            |.|.:                         .:::..:::.:....|::.::  |:.|::||. ..
 Worm   129 ELDDM-------------------------FEIDIKLISTHFIQFFESKSSLENNQNKVLST-HF 167

  Fly   308 IYDKELVSVIGWAKQIPGFIDLPLND------------------------QMKLLQVSW------ 342
            |....|:.|...|...|.:| ||.||                        ...:||..|
 Worm   168 IIRFSLLEVAFRAFGKPTYI-LPNNDIIDVSKLDKVYQHLETGEDERGKNSQVILQRFWQMNEKT 231

  Fly   343 --AEILTLQLTFRSLPFNGKLCFATDVWMDEHLAKECGYTEFYYHCVQIAQRME-RISPRREEY- 403
              .|:..:.|......|   || |...|       :.|.......|::..|||. ::.....||
 Worm   232 MKTEVFPVNLDQSEFLF---LC-ALIYW-------DFGIENQSEKCLEECQRMRTQVLKELTEYE 285

  Fly   404 ---YLLKALLLANCDILLDDQSSLRAFRDT-ILNSLNDVVYLLRHSSAVSHQQQL 454
               |               .::.||..:.. ||.:|...:.:::||..:|:...|
 Worm   286 KSNY---------------PENELRVAQVIGILQALQKTLDVIQHSGYISNVYNL 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	35/92 (38%)
		NR_LBD	237..493	CDD:472173	46/258 (18%)
nhr-108	NP_506987.1	ZnF_C4	9..75	CDD:197701	27/64 (42%)
		HOLI	134..309	CDD:214658	38/202 (19%)