Protein Alignment ERR and nhr-12

DIOPT Version :9

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001122983.1
• Gene: nhr-12 / 179403
• WormBaseID: WBGene00003611
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 423
• Identity: 100/423 - (23%)
• Similarity: 168/423 - (39%)
• Gaps: 93/423 - (21%)

  Fly   127 CLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNECEINKRRRKACQACRFQKCLLMG 191
            |.||.:|..|.|:|..:|.||.|||:|::..:.:|.|.|...||::...|..|::||:.||:.:|
 Worm    47 CAVCNEVGDGLHFGAEACRACTAFFRRSVALSKKYECRAGRNCEVSSNIRCMCRSCRYDKCIEVG 111

  Fly   192 MLKEGVRLDRVRG----------GRQKYRRNPVSNSYQTMQLLYQSNTTSLCDVKI-----LEVL 241
            |..|.|:..|...          .:.:.|| |:.|.....|.....:|::..|..|     :...
 Worm   112 MNPECVQNRRENDTPKADLQFDTSKTEIRR-PIPNFNIVPQASAVPSTSNFMDFSIFKDTPISNF 175

  Fly   242 NSYEPDALSVQTPPPQVHT------TSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPNE 300
            :::.|.:|...:..|.:.|      ..|..|:..::...|...      .|..|||   ...|..
 Worm   176 SAFSPASLPGLSSSPSLETMPLLERMRINYDKMENARNVIHRR------EGENIFQ---QKVPRA 231

  Fly   301 I-LSVLSDIYDKELVSVIGWAKQIPGFID---LPLNDQMKLLQVSWAEILTLQLTFRSLPF--NG 359
            | ....:::..||:..|..|.:..  |.|   ||::.:..|.|..:.....|:..|.::..  :|
 Worm   232 ITFREATEVTTKEVSLVADWIEWC--FDDFGLLPVDQKTILFQNFFVFFCMLERAFMTVKSGRDG 294

  Fly   360 KLCFATDVWMD----EHLAKEC----GYTEFYYHCVQIAQRMERISPRRE--------------- 401
            .:..|:..::|    |...|||    |.|.     .:||:....|.|..|
 Worm   295 IVVMASKDYIDYDNLEGFFKECNSGTGGTP-----AEIAKLCRLIRPSFELQKRSLINLMRLENV 354

  Fly   402 ---EYYLLKALLLANCDILLDDQSSL-----RAFRDTILNSLNDVVYLLR----HSSAVSHQQQL 454
               |::.|..:|.  .|..|:.||..     |..:..:   ..::.:.||    |...:.....:
 Worm   355 DSYEFFALCVMLF--WDFGLEGQSDECNEVGRRVKHRV---TREMTFYLRNVKKHEEPLYRMASV 414

  Fly   455 LLLLPSLRQADDILRRFWRGIARDEVITMKKLF 487
            :.:||||::|   :|||      .|.|.|..:|
 Worm   415 VSILPSLQRA---VRRF------QEDIEMANIF 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	33/99 (33%)
		NR_LBD	237..493	CDD:299703	63/303 (21%)
nhr-12	NP_001122983.1	ZnF_C4	46..115	CDD:197701	27/67 (40%)
		Hormone_recep	225..431	CDD:278530	48/229 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910