Protein Alignment ERR and nhr-43

DIOPT Version :9

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_502254.1
• Gene: nhr-43 / 178121
• WormBaseID: WBGene00003633
• Length: 449
• Species: Caenorhabditis elegans
• Alignment Length: 420
• Identity: 93/420 - (22%)
• Similarity: 167/420 - (39%)
• Gaps: 88/420 - (20%)

  Fly   112 AGAGSGSVRDELRRLCLVCGDVASGF-HYGVASCEACKAFFKRTIQGNIEYTC-PANNECEINKR 174
            :.:.|.:|.|.....|.||.....|. |:|:..|.||.|||:|::.....:.| ...|:||:|..
 Worm    32 SSSSSPTVADPSNIHCRVCERRYDGSQHFGIDICRACAAFFRRSVAVKKTFVCRRGTNKCELNTV 96

  Fly   175 RRK-ACQACRFQKCLLMGMLKEGVRLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTS---LC-D 234
            .|| .||.||:.:|||:|:     .:|.|.|.|........|......:...:|:|.|   .| |
 Worm    97 SRKTTCQKCRWMRCLLVGL-----NVDAVVGRRSPDHVKTTSRDESVKKEDEESDTGSEGKSCED 156

  Fly   235 VKILEVLNSYEPD-ALSVQTP-----PPQVHTT--SITN------DEASSSSGSIKL-------E 278
            :.:...:..::.. :.||..|     .|.::||  |:.|      :|.:.|...::|       :
 Worm   157 MDVSHPIEQFQQQISFSVHRPIPTIGNPNIYTTRASLINKVLINYNEFTKSRLDVELSLKHMQQD 221

  Fly   279 SSVVTPNGTCIFQNNNNNDPNEILSVLSDIYDKELVSVIGWAKQ-IPGFIDLPLNDQMKL----L 338
            |.|....|..|.....        .::|:||.|:...:..:.|. ...:.:..:.:|.::    .
 Worm   222 SKVFGSTGIPIVPATR--------EIISEIYQKQFGLLHIFLKNTFDEYAECDVQEQKRICAMFY 278

  Fly   339 QVSWAEILTLQLTFRSLPFNGK-----LCFATDVWMDEH-----LAKECGYTEFYYHCVQ----- 388
            .|.| ||.:...|:|::|...:     :|..| .::|..     |....|..|.....|:
 Worm   279 PVLW-EIESCYWTYRNMPVQPEYETLMMCTQT-TYIDSKNVRYWLGNTTGLNESDIQAVEARLEN 341

  Fly   389 --------IAQRMERISPRREEYYLLKALLL------ANCDILLDDQSSLRAFRDTILNSLNDVV 439
                    :.:.|.::..:..|:..|.||.:      ..|  :.:|::  ...||.:.:.|:
 Worm   342 LLTKARNLVLEPMHKLIIKEFEFITLLALNIWAPRNHRGC--VSEDRA--EQVRDALFDDLH--- 399

  Fly   440 YL----LRHSSAVSHQQQLLLLLPSLRQAD 465
            ||    |:.....|...:::.|...::.||
 Worm   400 YLYCDGLKIDKYSSRMGEMMCLHTEVQNAD 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	34/98 (35%)
		NR_LBD	237..493	CDD:299703	52/288 (18%)
nhr-43	NP_502254.1	ZnF_C4	47..118	CDD:197701	28/75 (37%)
		Hormone_recep	231..428	CDD:278530	36/213 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910