Protein Alignment ERR and nhr-10

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_498554.1
• Gene: nhr-10 / 175993
• WormBaseID: WBGene00003609
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 103/397 - (25%)
• Similarity: 167/397 - (42%)
• Gaps: 81/397 - (20%)

  Fly    99 GGGTSGGNATNASAGAGSGSVRDELRRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTC 163
            |||.|..|::             :...:||||.|:::|:||||.||..||.||:|||..|..::|
 Worm     3 GGGPSSNNSS-------------QPEEVCLVCSDISTGYHYGVPSCNGCKTFFRRTIMKNQTFSC 54

  Fly   164 PANNECEINKRRRKACQACRFQKCLLMGMLKEGVRLDR-VRGGRQKYRRNP-------------- 213
            ....:|.::|..|.||:.|||:|||.:||.:..::.:| ..|..::.||.|
 Worm    55 QFQGKCPVDKSIRCACRHCRFEKCLQVGMDRNAIQQNRDPIGYTKRTRRYPPIKKVEASDECSPA 119

  Fly   214 -VS---NSYQTMQLLYQSNTTSLCDVKILEVLNSYEPDALSVQTPPPQVHTTSITNDEASSSSGS 274
             ||   .|......|..|.....|.:::.|    |.|....::.    |.:..:..||.
 Worm   120 MVSENDRSEDNFLTLLSSTEQKCCALRLAE----YMPSRTLIEA----VVSDCLLTDEV------ 170

  Fly   275 IKLESSVVTPN---GTCIFQNNNNNDPNEILSVLSDI---YDKELVSVIGWAKQIPGFIDLPLND 333
            ...|.::::|.   .:..|.|.            ||.   ::::...:|.|||.:|.|..||..|
 Worm   171 FMAEHAILSPRHRVTSLRFANQ------------SDYHYWHERDWFVMIEWAKTLPVFQSLPFTD 223

  Fly   334 QMKLLQVSWAEILTLQLTFRSLPFNG--KLCFATDVWMDE--HLAKECGYTEFYYHCV-QIAQRM 393
            ::.||:.|.....:|...|.| |.:|  .:.|....:.|.  ...:..|:.:..|..: |:.:.|
 Worm   224 KLALLRHSAITYPSLVHVFNS-PDHGLDTIVFPDGAYFDRTPEPTRPLGFNKKKYQMLDQLLKPM 287

  Fly   394 ERISPRREEYYLLKALLLANCDILLDD-----QSSLRAFRDTILNSLNDVVYLLRHSSAVSHQQQ 453
            ..:.....|:...||:...|.|  .||     :.:|...|..|.|:|  ..|:::...|.....:
 Worm   288 RSMEIDMTEFAAFKAIFFLNPD--ADDVDSNAKKTLSDGRSAITNAL--YRYMVKKKGAEDAGDR 348

  Fly   454 L--LLLL 458
            .  ||||
 Worm   349 FGRLLLL 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	41/114 (36%)
		NR_LBD	237..493	CDD:472173	53/240 (22%)
nhr-10	NP_498554.1	NR_DBD_HNF4A	18..93	CDD:143518	34/74 (46%)
		HOLI	200..359	CDD:214658	41/161 (25%)