Protein Alignment ERR and nhr-80

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_871630.1
• Gene: nhr-80 / 175167
• WormBaseID: WBGene00003670
• Length: 504
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 98/460 - (21%)
• Similarity: 173/460 - (37%)
• Gaps: 101/460 - (21%)

  Fly   114 AGSGSVRDELRRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTC-PANNECEINKRRRK 177
            |.|.|.|      ||:|...|:|||:...||.||.|||:||:.....:.| ...::|.::....:
 Worm    23 ASSSSTR------CLICSAQATGFHFEAQSCSACAAFFRRTVALTKSFKCITGRDDCNVHYSMHQ 81

  Fly   178 ACQACRFQKCLLMGMLKEGV--RLDRVRGGRQKYRRNPVSNSYQTMQLLYQSNTTSLCDVKILEV 240
            .|::||.:|||..||...||  :...:..||..:.::.:..:.:...:..|:.......|:.::|
 Worm    82 ICRSCRHKKCLSNGMKPGGVQPKKPNIETGRAFFTKSGLKRNKKFANVSPQTADEQKLVVEGVKV 146

  Fly   241 --LNSYEPDALS---------VQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPN--------- 285
              :...||::|.         ::||.|:        ..:||:|.|....::..||.
 Worm   147 PKIEVQEPNSLEDLEQDNEFVIKTPTPR--------KISSSTSFSASTTTNYSTPGPSPMAPCSA 203

  Fly   286 ----------------------------GTCIFQNNNNNDPNEILS--VLSDI---YDKELVSVI 317
                                        ||.:.||.:.....|.:.  |..|.   ....::.|.
 Worm   204 GPDVLTLFIREEMKLGERRRLLFSERAVGTLLGQNKHCPYKKEDIKPLVFHDFRLTIKTHIMLVY 268

  Fly   318 GWAKQIPGFIDLPLNDQMKLLQVSWAEILTLQLTFRSLPF---------NGKLCFATD----VWM 369
            .|.:..|...:|...|:|.||:.:......|..:|.|...         ||......|    .|.
 Worm   269 EWLQTWPELQELDDFDRMSLLRKAVLIHFLLDPSFLSYQIGEPDKLIMQNGGFISTADHHGVGWE 333

  Fly   370 DEHLAKECGYTEFYYHCV-----QIAQRMERISPRREEYYLLKALLLANCDILLDDQSSLRAFRD 429
            ||.........::|...:     :|...||.:....||:..||||.......    ::...|.|.
 Worm   334 DETDISGENKRKYYVPIMKQITDEIMPAMEAMKITFEEFVALKALACFQGGF----ENVSEAKRH 394

  Fly   430 TILNSLNDVVYLLRHSSAVSHQQQ--------LLLLLPSLRQADDILRRFWRGIARDEVITMKKL 486
            .|...:|.::..| |:..:.:.::        ::|:|.::..|.:...:..|.|....:..:.||
 Worm   395 LITQQVNRIMTSL-HTHYLENSEEKIAERFGTIVLMLSNIFTAGNDFVQNHREIDIFHIWDLDKL 458

  Fly   487 FLEML 491
            .|::|
 Worm   459 VLQLL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	30/98 (31%)
		NR_LBD	237..493	CDD:472173	62/334 (19%)
nhr-80	NP_871630.1	ZnF_C4	30..98	CDD:197701	26/67 (39%)
		HOLI	261..436	CDD:214658	35/179 (20%)