Protein Alignment ERR and Nr3c1

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_006525721.1
• Gene: Nr3c1 / 14815
• MGIID: 95824
• Length: 793
• Species: Mus musculus
• Alignment Length: 520
• Identity: 152/520 - (29%)
• Similarity: 227/520 - (43%)
• Gaps: 109/520 - (20%)

  Fly    22 IKQEVDTPSASCFSPSSKSTATQSGTN--GLKSSPSVSPERQLCSSTTSLSCDLHNVSLSNDGDS 84
            ||||...| ..|       .|:.||||  |.|.| ::|......|.......|::..|||...|.
Mouse   309 IKQEKLGP-VYC-------QASFSGTNIIGNKMS-AISVHGVSTSGGQMYHYDMNTASLSQQQDQ 364

  Fly    85 -------------------LKGSG----TSGG--NGGG----GGGGTSGGNATNASAGAGSGS-V 119
                               .:|||    ||.|  |..|    ..|.:|.|...:.|:...|.| .
Mouse   365 KPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTA 429

  Fly   120 RDELRRLCLVCGDVASGFHYGVASCEACKAFFKRTIQG-NIEYTCPANNECEINKRRRKACQACR 183
            .....:|||||.|.|||.||||.:|.:||.||||.::| ...|.|...|:|.|:|.|||.|.|||
Mouse   430 TGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCIIDKIRRKNCPACR 494

  Fly   184 FQKCLLMGMLKEGVRL-DRVRGGRQK---YRRNPVSNSYQTM------QLLYQSNTTSLCDVKIL 238
            ::|||..||..|..:. .:::|.:|.   ..::...|:.:|:      ||     |.:|  |.:|
Mouse   495 YRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQL-----TPTL--VSLL 552

  Fly   239 EVLNSYEPDALSVQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPNEILS 303
            ||:   ||:.|..                        ..:|||  |:...           .|::
Mouse   553 EVI---EPEVLYA------------------------GYDSSV--PDSAW-----------RIMT 577

  Fly   304 VLSDIYDKELVSVIGWAKQIPGFIDLPLNDQMKLLQVSWAEILTLQLTFRSL--PFNGKLCFATD 366
            .|:.:..:::::.:.|||.||||.:|.|:|||.|||.||..::...|.:||.  .....||||.|
Mouse   578 TLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPD 642

  Fly   367 VWMDE-HLAKECGYTEFYYHCVQIAQRMERISPRREEYYLLKALLLANC--DILLDDQSSLRAFR 428
            :.::| .:...|.|.: ..|.:.|:..::|:....|||..:|.|||.:.  ...|..|......|
Mouse   643 LIINEQRMTLPCMYDQ-CKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIR 706

  Fly   429 DTILNSLNDVVYLLRHSSAVSHQQ--QLLLLLPSLRQADDILRRFWRGIARDEVITMKKLFLEML 491
            .|.:..|...:.....:|:.:.|:  ||..||.|:....:.|..:......|:.::::  |.|||
Mouse   707 MTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIE--FPEML 769

  Fly   492  491
            Mouse   770  769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	42/100 (42%)
		NR_LBD	237..493	CDD:472173	68/262 (26%)
Nr3c1	XP_006525721.1	GCR	27..418	CDD:426625	32/117 (27%)
		NR_DBD_GR_PR	433..511	CDD:143546	40/77 (52%)
		NR_LBD_GR	547..793	CDD:132761	70/268 (26%)