DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ERR and ar

DIOPT Version :9

Sequence 1:	NP_648183.3	Gene:	ERR / 38912	FlyBaseID:	FBgn0035849	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_002941888.3	Gene:	ar / 100489816	XenbaseID:	XB-GENE-479429	Length:	788	Species:	Xenopus tropicalis

Alignment Length:	383	Identity:	111/383 - (28%)
Similarity:	178/383 - (46%)	Gaps:	79/383 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 RDEL---------RRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNECEINKRR 175
            ||.|         ::.||:|||.|||.|||..:|.:||.||||..:|..:|.|.:.|:|.|:|.|
Frog   411 RDHLLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFR 475

  Fly   176 RKACQACRFQKCLLMGMLKEGVRLDRVRG--GRQKYRRNPVSNSYQTMQLLYQSNTTSL----CD 234
            ||.|.:||.:||...||.....:|.::..  .:::...:||... .:..|........|    |.
Frog   476 RKNCPSCRLRKCYEAGMTLGARKLKKLGNLKAQEELEGSPVQGE-GSKDLAPGMGIPQLEGYSCQ 539

  Fly   235 VKILEVLNSYEPDALSVQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPN 299
            ...|.||.:.||                                  ||...|      ::||.|:
Frog   540 PIFLNVLEAIEP----------------------------------VVVCAG------HDNNQPD 564

  Fly   300 E---ILSVLSDIYDKELVSVIGWAKQIPGFIDLPLNDQMKLLQVSWAEILTLQLTFRSLP-FNGK 360
            .   :||.|:::.:::||.|:.|||.:|||.:|.::|||.::|.||..::...:.:||.. .|.:
Frog   565 SFALLLSSLNELGERQLVHVVKWAKALPGFRNLHVSDQMTVIQYSWMGLMIFAMGWRSFKNVNSR 629

  Fly   361 -LCFATDVWMDEHLAKECGYTEFYYHCVQIAQRME-----RISPRREEYYLLKALLLANCDIL-- 417
             |.||.|:..:|:...:   :..|..||::....:     :|:|  ||:..:|||||.:  |:
Frog   630 MLYFAPDLVFNEYRMHK---SRMYSQCVRLRHLSQEFGWLQITP--EEFLCMKALLLFS--IIPV 687

  Fly   418 --LDDQSSLRAFRDTILNSLNDVVYLLRHSSAVSHQQ--QLLLLLPSLRQADDILRRF 471
              |.||......|...:..|:.|:...|::.|.|.::  ||..||.|::.....|.:|
Frog   688 EGLKDQKCFDELRMNYIKELDRVISCKRNNPASSSRRFFQLTKLLDSVQPIARELHQF 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	40/106 (38%)
ERR	NP_648183.3	NR_LBD	237..493	CDD:299703	67/251 (27%)
ar	XP_002941888.3	Androgen_recep	6..376	CDD:396645
		NR_DBD_AR	422..503	CDD:143547	36/80 (45%)
		NR_LBD_AR	541..786	CDD:132758	67/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48092
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010