Protein Alignment ERR and esrrg

DIOPT Version :10

• Sequence 1: NP_648183.3
• Gene: ERR / 38912
• FlyBaseID: FBgn0035849
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_012818028.1
• Gene: esrrg / 100101684
• XenbaseID: XB-GENE-486172
• Length: 484
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 195/520 - (37%)
• Similarity: 257/520 - (49%)
• Gaps: 99/520 - (19%)

  Fly    20 LHIKQE-----------VDTPSAS----------CFSPSSKSTATQSGTNGLKSSPSVSPERQLC 63
            ||.::|           |.|.|.|          |...|.......|.::.:|:.|
 Frog    14 LHYEEEEMVYIHRHGVNVRTSSFSENKTLPSWLLCRMSSKDRHIDSSCSSYIKTEP--------- 69

  Fly    64 SSTTSLSCDLHNVSLSNDGDSLKGSGTSGGNGGGGG----------GGTSGGNATNASAGAGSGS 118
            ||..||:..:::.|.....|: .||.:|..||...|          .|..|...........|.:
 Frog    70 SSPASLTDSINHHSPGGSSDA-SGSYSSTMNGHQNGLDSPPLYPSATGLGGNGPVRKRYDDCSST 133

  Fly   119 VRDEL------------RRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPANNECEI 171
            :.:|.            :||||||||:|||:||||||||||||||||||||||||:|||.|||||
 Frog   134 IAEESQTKCEYMLNAMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEI 198

  Fly   172 NKRRRKACQACRFQKCLLMGMLKEGVRLDRVRGGRQKY-RRNPVSNS-YQTMQLLYQSNTTSLCD 234
            .|||||:||||||.|||.:||||||||||||||||||| ||....|| |...||:..:....
 Frog   199 TKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPY--- 260

  Fly   235 VKILEVLNSYEPDALSVQTPPPQVHTTSITNDEASSSSGSIKLESSVVTPNGTCIFQNNNNNDPN 299
            .||:..|...||:.:... |.|.|..:.|
 Frog   261 NKIVSHLLVAEPEKIYAM-PDPTVPDSDI------------------------------------ 288

  Fly   300 EILSVLSDIYDKELVSVIGWAKQIPGFIDLPLNDQMKLLQVSWAEILTLQLTFRSLPFNGKLCFA 364
            :.|:.|.|:.|:|||.:|||||.||||..|.|.|||.|||.:|.|||.|.:..|||.|..:|.:|
 Frog   289 KALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGIVNRSLSFEDELVYA 353

  Fly   365 TDVWMDEHLAKECGYTEFYYHCVQIAQRMERISPRREEYYLLKALLLANCDIL-LDDQSSLRAFR 428
            .|..|||..:|..|..|.....:|:.::.:.:...:||:..|||:.|||.|.: ::|..:::..:
 Frog   354 EDYIMDEDQSKLAGLLELNNAILQLVKKYKTMKLEKEEFVTLKAIALANSDSMHIEDIEAVQKLQ 418

  Fly   429 DTILNSLNDVVYLL-RHSSAVSHQQQLLLLLPSLRQADDILRRFWRGIARDEVITMKKLFLEMLE 492
            |.:..:|.|  |.. :|........:||:.||.|||......:.:..|..:..:.|.||||||||
 Frog   419 DVLHEALQD--YEAGQHIEDPRRAGKLLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 481

  Fly   493  492
             Frog   482  481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERR	NP_648183.3	NR_DBD_ERR	121..217	CDD:143544	79/108 (73%)
		NR_LBD	237..493	CDD:472173	83/258 (32%)
esrrg	XP_012818028.1	NR_DBD_ERR	150..244	CDD:143544	78/93 (84%)
		NR_LBD_ERR	263..482	CDD:132744	83/258 (32%)