Protein Alignment Uxs and MAT2B

DIOPT Version :9

• Sequence 1: NP_648182.1
• Gene: Uxs / 38911
• FlyBaseID: FBgn0035848
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_037415.1
• Gene: MAT2B / 27430
• HGNCID: 6905
• Length: 334
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 45/225 - (20%)
• Similarity: 80/225 - (35%)
• Gaps: 53/225 - (23%)

  Fly    73 REQKAELQRTRENLARLEEQVRSLQTSTPRKYPKVKYLNYKNRKRILITGGAGFVGSHLVDDLMV 137
            ||::..:.....:...:||:|                 |..|| |:|:||..|.:|..:
Human     4 REKELSIHFVPGSCRLVEEEV-----------------NIPNR-RVLVTGATGLLGRAV------ 44

  Fly   138 QGHEVIVVDNFFT---GRKRNVEHWLGHENFELIH-------HDIVNPLFIEIDEIYHLASPASP 192
              |:....:|:..   |.:|      ....||.::       |.|::.....:  |.|.|:...|
Human    45 --HKEFQQNNWHAVGCGFRR------ARPKFEQVNLLDSNAVHHIIHDFQPHV--IVHCAAERRP 99

  Fly   193 PHYMYNPVKTIKTNTMGTINVLGLAKRVMAKVLIASTSEVYG--DPTVH----PQPETYWGHVNP 251
            ......|....:.|...:.|:...|..|.|.::..|:..|:.  :|...    |.|...:|....
Human   100 DVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKL 164

  Fly   252 IGPRACYDE--GKRVSETLSYAYAKQEKVQ 279
            .|.:|..:.  |..|.. :...|.:.||::
Human   165 DGEKAVLENNLGAAVLR-IPILYGEVEKLE 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uxs	NP_648182.1	WcaG	116..424	CDD:223528	37/182 (20%)
		UGD_SDR_e	116..419	CDD:187541	37/182 (20%)
MAT2B	NP_037415.1	dTDP_HR_like_SDR_e	30..316	CDD:187564	37/181 (20%)
		Required for interaction with MAT2A. /evidence=ECO:0000269|PubMed:25075345	319..334

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900