DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uxs and Uxs1

DIOPT Version :9

Sequence 1:	NP_648182.1	Gene:	Uxs / 38911	FlyBaseID:	FBgn0035848	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_038938945.1	Gene:	Uxs1 / 246232	RGDID:	628680	Length:	459	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	257/385 - (66%)
Similarity:	307/385 - (79%)	Gaps:	14/385 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LQRSLQMAYEEQSSLIREQKAELQRTRENLARLEEQVRSLQTSTPRKYPKVKYLNYKNRKRILIT 121
            |.||:|    |...|..|.|.|     |.:..|.|::|.|:.|..:|||.||:|:.|:|||||||
  Rat    78 LNRSIQ----ENGELKIESKIE-----EIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILIT 133

  Fly   122 GGAGFVGSHLVDDLMVQGHEVIVVDNFFTGRKRNVEHWLGHENFELIHHDIVNPLFIEIDEIYHL 186
            ||||||||||.|.||:.||||.||||||||||||||||:||||||||:||:|.||:||:|:||||
  Rat   134 GGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHL 198

  Fly   187 ASPASPPHYMYNPVKTIKTNTMGTINVLGLAKRVMAKVLIASTSEVYGDPTVHPQPETYWGHVNP 251
            |||||||:|||||:||:||||:||:|:|||||||.|::|:||||||||||.||||.|.|||||||
  Rat   199 ASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHVNP 263

  Fly   252 IGPRACYDEGKRVSETLSYAYAKQEKVQVRVARIFNTYGPRMHMNDGRVVSNFILQALRNETITV 316
            |||||||||||||:||:.|||.|||.|:|||||||||:||||||||||||||||||||:.|.:||
  Rat   264 IGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTV 328

  Fly   317 YGNGKQTRSFQYVSDLVDGMIALMASNYTQPVNLGNPVEQTIGEFAEIIKKLVGGPSVIKQSKAM 381
            ||:|.|||:||||||||:|::|||.||.:.|||||||.|.||.|||::||.|||..|.|:.....
  Rat   329 YGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEA 393

  Fly   382 EDDPQRRKPDITRARQLLHWEPKVPLETGLQRTISYFRNELARSDRFQESSNKYFDTHTP 441
            :||||:|||||.:|:.:|.|||.||||.||.:.|.|||.||.     .:::|:|.....|
  Rat   394 QDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELE-----YQANNQYIPKPKP 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uxs	NP_648182.1	WcaG	116..424	CDD:223528	231/307 (75%)
Uxs	NP_648182.1	UGD_SDR_e	116..419	CDD:187541	227/302 (75%)
Uxs1	XP_038938945.1	UXS1_N	<64..117	CDD:403108	16/47 (34%)
Uxs1	XP_038938945.1	UGD_SDR_e	128..431	CDD:187541	227/302 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342034
Domainoid	1	1.000	472	1.000	Domainoid score	I421
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41609
Inparanoid	1	1.050	519	1.000	Inparanoid score	I1228
OMA	1	1.010	-	-		QHG61048
OrthoDB	1	1.010	-	-		D289613at33208
OrthoFinder	1	1.000	-	-		FOG0002011
OrthoInspector	1	1.000	-	-		oto95633
orthoMCL	1	0.900	-	-		OOG6_100713
Panther	1	1.100	-	-	LDO	PTHR43078
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1322
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.810