Protein Alignment Uxs and hsd-1

DIOPT Version :10

• Sequence 1: NP_648182.1
• Gene: Uxs / 38911
• FlyBaseID: FBgn0035848
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_493402.1
• Gene: hsd-1 / 189371
• WormBaseID: WBGene00012394
• Length: 462
• Species: Caenorhabditis elegans
• Alignment Length: 357
• Identity: 71/357 - (19%)
• Similarity: 138/357 - (38%)
• Gaps: 92/357 - (25%)

  Fly    57 LQRSLQMAYEEQSSLIREQKAELQRTRENLARLEEQVRSLQTSTPRKYPKVKYLNYKNRKRILIT 121
            |::.:..::...:||    :|.|:.        |::::.::...||.:            ::|||
 Worm    10 LKKGIHRSWNRMTSL----EAGLEE--------EKEIKIVEEPEPRPW------------KVLIT 50

  Fly   122 GGAGFVGSHLVDDLMVQGHEV--------------------------------------IVVDNF 148
            ||||    ||.::|:.:..|:                                      ||:.:.
 Worm    51 GGAG----HLAENLVAKLEEMTRDSIRPKIREMLEKEMPAVISTKVDKEVEKRLPMYIQIVLVDV 111

  Fly   149 FTGRKRNVEHWLGHENFELIHHDIVNPLFIEIDEIYHLASPASPPHYMYNPVKTIKTNTMGTINV 213
            ...|.|.::|.:............:.....::|.:||||:......|..:....:..|.:||:|:
 Worm   112 LEPRGRVLKHHVAFVKCSFDDECTMKTALEQVDTVYHLAAVGMTGQYARDRKACMDINAVGTMNL 176

  Fly   214 LGLAKR--VMAKVLIASTSEVY-GDPTVHP-----QPETYWGHVNPIGPRACYDEGKRVSETLSY 270
            |..|:.  |...:..:|...|: |:|..:.     .|:.::.:         |.|.|..:|.: .
 Worm   177 LIWARNSGVQRFIYTSSVGVVFSGEPMYNATEEVGYPDDFYNY---------YCESKAHAERI-V 231

  Fly   271 AYAKQEKVQVRVARIFNTYGPRMHMNDGRVVSNFILQALRNETITVYGNGKQTRSFQYVSDLVDG 335
            ..|...:::..|.|....|||.......||| .|:|..:...|....|...||: ...|::.:.|
 Worm   232 QKASGHRMRTTVLRFNGIYGPGEKRVTERVV-KFMLTGMWIATCKPNGVEAQTQ-LSSVANCIQG 294

  Fly   336 MI----ALMASNYTQPVNLGNPVEQT-IGEFA 362
            ::    ||..|: |....:.|.:::| :|.|:
 Worm   295 LVKAELALRWSD-TPHGQIYNIMDKTPVGTFS 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uxs	NP_648182.1	UGD_SDR_e	116..419	CDD:187541	63/298 (21%)
hsd-1	NP_493402.1	Rossmann-fold NAD(P)(+)-binding proteins	47..407	CDD:473865	63/296 (21%)