Protein Alignment Uxs and Nsdhl

DIOPT Version :10

• Sequence 1: NP_648182.1
• Gene: Uxs / 38911
• FlyBaseID: FBgn0035848
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_035071.3
• Gene: Nsdhl / 18194
• MGIID: 1099438
• Length: 362
• Species: Mus musculus
• Alignment Length: 361
• Identity: 78/361 - (21%)
• Similarity: 140/361 - (38%)
• Gaps: 74/361 - (20%)

  Fly   116 KRILITGGAGFVGSHLVDDLMVQGHEVIVVDNFFTGRKRNVEHWLGHENFELIHHDIVNPLFIEI 180
            |:..:.||:||:|.|:|:.|:.:|:.|.|.|.........|:.::|    :|.:...:.|....:
Mouse    27 KKCTVIGGSGFLGQHMVEQLLERGYTVNVFDIHQGFDNPRVQFFIG----DLCNQQDLYPALKGV 87

  Fly   181 DEIYHLASPASPPHYMYNPVKTIKTNTMGTINVLGLAKR--VMAKVLIASTSEVY---------G 234
            ..::|.   ||||.|..|.....:.|.:||..|:...:.  |...:|.:|.|.|:         .
Mouse    88 STVFHC---ASPPPYSNNKELFYRVNFIGTKTVIETCREAGVQKLILTSSASVVFEGVDIKNGTE 149

  Fly   235 DPTVHPQPETYWGHVNPIGPRACYDEGKRVSETLSYAYAKQEKVQVRVARIFNTYGPRMHMNDGR 299
            |.....:|..|:.....:..||..|........|:.|        :|...||   |||    |.:
Mouse   150 DLPYAMKPIDYYTETKILQERAVLDANDPKKNFLTAA--------IRPHGIF---GPR----DPQ 199

  Fly   300 VVSNFILQALRNETITVYGNGKQTRSFQYVSDLVDGMIALMASNYTQPVNLGNPVEQTIGE---- 360
            :|...|..|.:.:...:.|||:....|.:|.::|.|.| |.|.:.:|...||........:
Mouse   200 LVPILIDAARKGKMKFMIGNGENLVDFTFVENVVHGHI-LAAEHLSQDAALGGKAFHITNDEPIP 263

  Fly   361 FAEIIKKLVGGPS-----------------------VIKQSKAMEDDPQRRKPDIT--------- 393
            |...:.:::.|.:                       |:..|..::..|......:.
Mouse   264 FWTFLSRILTGLNYEAPKYHIPYWMAYYLAFLLSLLVMVVSPLIQIQPTFTPIRVALAGTFHYYS 328

  Fly   394 --RARQLLHWEPKVPLETGLQRTISYFRNELARSDR 427
              :|::|..:.|.|.::..::||:..|.:  .|.|:
Mouse   329 CEKAKKLFGYRPLVTMDEAVERTVQSFHH--LRKDK 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uxs	NP_648182.1	UGD_SDR_e	116..419	CDD:187541	75/351 (21%)
Nsdhl	NP_035071.3	3b-HSD-NSDHL-like_SDR_e	29..355	CDD:187673	74/348 (21%)
		Prevents secretion from ER. /evidence=ECO:0000269|PubMed:14506130	359..362		1/2 (50%)