DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and adgre5b.3

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_005160275.1	Gene:	adgre5b.3 / 792970	ZFINID:	ZDB-GENE-121214-275	Length:	756	Species:	Danio rerio

Alignment Length:	264	Identity:	47/264 - (17%)
Similarity:	107/264 - (40%)	Gaps:	47/264 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 LIITMICFVLTIAVYLYIKKLRNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGI-CSPAGYSSHF 289
            |::::||.:|.|..:.:.:.::.......:...|..||..|:.:....:..|.: |:......||
Zfish   474 LVLSLICLILCILTFRFCRSIQGTRNSIHLHLSVCLFIADLVFLCGISSTHNQVACAIVAGLLHF 538

  Fly   290 FRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWN 354
            |.:::..|:.:.....::::..:......:.:: |.........|::.|...|.:.:..|  :..
Zfish   539 FFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYM-YAVGYGVPLVIVSISAIAVPKGYGTD--RHC 600

  Fly   355 WLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFT--NEEEGRI 417
            ||.|.|::..|         .:|  |...:...|:.:|.:|...:..      ||:  |.:..::
Zfish   601 WLSLEGYLILS---------FFI--PVCIIVILNITVFIITVWKLAL------KFSSLNPDLSKL 648

  Fly   418 NCINFDSQTYLQFLRLSI----VMGLTWIFNVIPY-----SARLHIFWEWVGIISEYFHSAFGIV 473
            :.|.       .||..::    |:|.:|:|....:     ...|::|     ||   .:|..|.:
Zfish   649 HKIR-------SFLATAVAQLCVLGGSWVFGFFLFQKNGTEVMLYLF-----II---LNSLQGAL 698

  Fly   474 LFVL 477
            :|::
Zfish   699 IFIM 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804
adgre5b.3	XP_005160275.1	EGF_CA	32..>62	CDD:214542
		EGF_CA	72..105	CDD:214542
		EGF_CA	<121..152	CDD:214542
		EGF_CA	154..188	CDD:214542
		GPS	416..460	CDD:197639
		7tm_2	466..699	CDD:278432	46/259 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910