DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrf4

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_001276428.1 Gene:Adgrf4 / 78249 MGIID:1925499 Length:698 Species:Mus musculus


Alignment Length:325 Identity:65/325 - (20%)
Similarity:118/325 - (36%) Gaps:103/325 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 IRHRCTSHISPGSLEIL---------IITMICFV-LTIAVYLYIKKLRNVTGKCIVCCIV----- 259
            ::.||....:..|..||         |:..|.|: |:|:::            .:|.|:|     
Mouse   378 VKCRCRHTKAVTSFSILMSSKPVKNTILNHITFIGLSISIF------------SLVLCLVIEAIV 430

  Fly   260 -SRFIQCLIMILDHLNLLNGICSPAGYSSHFFRMASNLWLSVISYHTWKV-LTSLNRVDPNYRFL 322
             ||.:...|..:.|:.::| |......::.:|.:.||...:|...|.|.| :|.|      ..|.
Mouse   431 WSRVVVTEISYMRHVCIVN-IAVSLLTANVWFIIGSNFSANVQEDHKWCVAVTFL------CHFF 488

  Fly   323 RYNAFVW---STAAIMTGSIYIVNQIWENDPSKWNW-----LPLV-------------GFIRCSV 366
            ..:.|.|   ....|:.|.:.:..::.::......:     .|||             |:.|   
Mouse   489 FLSLFFWMLFKALLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVTVTEPGEGYTR--- 550

  Fly   367 KD-----WHPSVWIY-ISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQ 425
            ||     |:.:..:: .:.|:||:...|:.:....||..::...|.:|               ||
Mouse   551 KDACWLNWNQTKALFAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSK---------------SQ 600

  Fly   426 TYLQFLRLS-------IVMGLTWIFNVIPYSARLHIFWEWVGIISEYFHSAFGIV-----LFVLL 478
            ......|:|       .::||||.|.:......:|:          .||..|.::     .|:||
Mouse   601 DMAIVFRISKNVAILTPLLGLTWGFGLTTLLEGVHL----------VFHIIFALLNAFQGFFILL 655

  Fly   479  478
            Mouse   656  655

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804 0/3 (0%)
Adgrf4NP_001276428.1 GPS 351..394 CDD:366827 3/15 (20%)
7tm_GPCRs 402..669 CDD:391938 60/301 (20%)
TM helix 1 405..429 CDD:341315 7/35 (20%)
TM helix 2 444..465 CDD:341315 4/21 (19%)
TM helix 3 479..501 CDD:341315 6/27 (22%)
TM helix 4 522..538 CDD:341315 3/15 (20%)
TM helix 5 560..583 CDD:341315 4/22 (18%)
TM helix 6 606..631 CDD:341315 7/24 (29%)
TM helix 7 636..661 CDD:341315 6/30 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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