Protein Alignment mthl7 and Adgrf1

DIOPT Version :9

• Sequence 1: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_006525183.1
• Gene: Adgrf1 / 77596
• MGIID: 1924846
• Length: 927
• Species: Mus musculus
• Alignment Length: 556
• Identity: 104/556 - (18%)
• Similarity: 193/556 - (34%)
• Gaps: 171/556 - (30%)

  Fly    22 ADIPGCNYYDTVDISYIERQNDSYLYDDIEIPASLTGYYEFRQFGDGSITPIEKHLRACVCSVRP 86
            ::|...:..:::.:|.:...|...:.|.|...||:|.:....|....:.:.:.|.|.: :.|:.|
Mouse   371 SNISSLSLANSLTVSNLTLMNVINIADHILDSASITNWTILLQDAKDASSQLLKTLES-ISSLIP 434

  Fly    87 CIRICCPAKNFLANGKCDDGLKEELARF---KPYIYFTYMDLQARVPLTDMAIIRDEFFDCDEMI 148
            .:.:   ..||  :||..|.....:.:.   :.|.|...|...|.:|:.....|..:.|......
Mouse   435 SMAL---PLNF--SGKFIDWKGTPVTQIQSTRGYNYQMEMRQNASLPIRGHVFIEPDQFQKSHPK 494

  Fly   149 YISDFNYFLEEVSIQIFNKCGLIVWFQDGKFWVT-------------VDLFME--------KQDY 192
            .|         :|:.......::...|.|..||.             .::|:.        .|..
Mouse   495 TI---------ISMASLTFGDILPITQRGNAWVNGPVISTLIQNYSISEIFLNFSKIKGNLTQPR 550

  Fly   193 CLYRHNFDSDFPKSMW-------------IIRHRCTSHIS----------PGS------------ 222
            |::     .||.:..|             .:..|| ||::          |.|
Mouse   551 CVF-----WDFSQLQWSNAGCQLVNETLDTVLCRC-SHLTSFSMLMSPFVPSSVVPVVKWITYIG 609

  Fly   223 LEILIITMI-CFVLTIAVYLYIKK-----LRNVTGKCIVCCIVSRFIQCLIMIL----DHLNLLN 277
            |.|.|.::| |.::....:...|:     .||:   |:|...||..|..:..|:    |.....:
Mouse   610 LSISIASLILCLIIESLFWKQTKRSQTSYTRNI---CLVNIAVSLLIADVWFIIAATVDPSVSPS 671

  Fly   278 GICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMT------ 336
            |:|..|.:.:|||.:|...|:.|:.     :|.:       ||.:    .|:...|:.|
Mouse   672 GVCVAAVFFTHFFYLAVFFWMLVLG-----ILLA-------YRII----LVFHHMALTTMMAIGF 720

  Fly   337 ----GSIYIV-----------NQIWENDPSKWNW----LPLVGFIRCSVKDWHPSVWIYISGPSL 382
                |...::           |....||....||    .||:.|:                .|:|
Mouse   721 CLGYGCPLLISIITLAVTQPSNSYKRNDVCWLNWSDKSKPLLAFV----------------VPAL 769

  Fly   383 ALSTFNVAMFALTAIYIRKV-KGGINKFTNEEEGRINCINFDSQTYLQ----FLRLSIVMGLTWI 442
            .:...|:.:..|.   :||: :..:.:..|::         |..|.::    .|.|:.::||||.
Mouse   770 TIVAVNLVVVLLV---LRKLWRPAVGERLNQD---------DKATAIRMGKSLLVLTPLLGLTWG 822

  Fly   443 FNV----IPYSARLHIFWEWVGIISEYFHSAFGIVL 474
            |.:    ..::...|:.:..:.....:|...|||:|
Mouse   823 FGIGTMANSHNLAWHVLFALLNAFQGFFIFCFGILL 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	36/223 (16%)
Adgrf1	XP_006525183.1	SEA	172..258	CDD:366610
		GPS	549..590	CDD:197639	8/46 (17%)
		7tm_GPCRs	603..866	CDD:391938	61/303 (20%)
		TM helix 1	603..626	CDD:341315	5/22 (23%)
		TM helix 2	641..663	CDD:341315	7/24 (29%)
		TM helix 3	675..702	CDD:341315	8/38 (21%)
		TM helix 4	716..736	CDD:341315	1/19 (5%)
		TM helix 5	757..786	CDD:341315	8/47 (17%)
		TM helix 6	803..829	CDD:341315	7/25 (28%)
		TM helix 7	834..859	CDD:341315	6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900