DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and Adgrd1

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_001070157.3	Gene:	Adgrd1 / 689257	RGDID:	1594795	Length:	903	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	54/320 - (16%)
Similarity:	122/320 - (38%)	Gaps:	49/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 YCLYRHNFD---SDFPKSMWIIRHRCTSHISPGSLEILIITMICFVLTIAVYLYIKKLRN----V 249
            :|.:..||.   ...|..:.:......|.||.....:.::.:...::|.||...:..:||    :
  Rat   569 HCTHLTNFAILMQVVPLKLTLGHQVALSSISYVGCSLSVLCLAATLVTFAVLSSVSTIRNQRYHI 633

  Fly   250 TGKCIVCCIVSRFIQCLIMILDHLNLLNGI--CSPAGYSSHFFRMASNLWLSVISYHTWKVLTSL 312
            ........:|::     :::|...::..|.  |.......|:|.:.:..|:.|...|.:.::..:
  Rat   634 HANLSFAVLVAQ-----VLLLISFSMEPGTVPCQVLAVLLHYFFLTAFAWMLVEGLHLYSMVIKV 693

  Fly   313 NRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPLVGFIRCSVKDWHPSVWIYI 377
            ...:.: :.|.|....|. ..::...|.:.:.:.........||        ||:.  .::|.::
  Rat   694 FGSEDS-KHLYYYGIGWG-CPLLICIISVSSSMDSYGTGDSCWL--------SVES--GAIWAFV 746

  Fly   378 SGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWI 442
             ||:|.:...|:.:.    :.:.:|...|:..:.:..|..:.....::.....|.   ::|.:|:
  Rat   747 -GPALLVIVVNIVIL----VAVTRVISHISTDSYKIHGDPSAFKLTAKAVAVLLP---ILGTSWV 803

  Fly   443 FNVIPYSARLHIFWEWVGIISEYFHSAFGIVLFVLLVL-----------KRSTWTLMMDS 491
            |.|:..|.|..:|.....|:    :|:.|:.:|:...|           |...|:|...|
  Rat   804 FGVLAVSDRALVFQYMFAIL----NSSQGLFIFLFHCLLNSEVRAAFKHKMKVWSLTSSS 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	4/24 (17%)
Adgrd1	XP_001070157.3	LamG	<173..273	CDD:304605
		GPS	539..579	CDD:280071	3/9 (33%)
		7tm_4	595..831	CDD:304433	44/264 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810