DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and adgrl2a

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_021335387.1 Gene:adgrl2a / 57987 ZFINID:ZDB-GENE-000607-49 Length:1520 Species:Danio rerio


Alignment Length:284 Identity:53/284 - (18%)
Similarity:101/284 - (35%) Gaps:72/284 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   226 LIITMICFVLTIAVYLYIKKL---RNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGI-------- 279
            :::::||..::|..:.:.:.|   ||...|.:          |:.:.:..|..|.||        
Zfish   871 IVVSLICLAMSIFTFCFFRGLQSDRNTIHKNL----------CINLFIAELIFLIGIDMTEPKLA 925

  Fly   280 CSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQ 344
            ||......|:|.:||..|:.:.....:.:|..:...:.:.|...|.|.....|.::..|..:  .
Zfish   926 CSIIAGILHYFFLASFAWMCLEGVQLYLMLVEVFESEYSRRKYFYMAGYLLPAVVVGVSAAV--D 988

  Fly   345 IWENDPSKWNWLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKF 409
            .......|..||.:         |.| .:|.:| ||...:...|:....:|...:.|....:...
Zfish   989 FRSYGTKKACWLRM---------DNH-FIWSFI-GPVTFIIMLNLIFLLITMYKMMKHSTSLKPD 1042

  Fly   410 TNEEEGRIN----CINF---------DSQTYLQF-----LRLSIVMGLTWIFNVIPYSARLHIFW 456
            ::..| .||    |..:         |::.:::.     ..|..::||||.|.:           
Zfish  1043 SSRLE-HINNYRVCDGYYNSDLPGYEDNKPFIKSWVMGGFALLCLLGLTWSFGL----------- 1095

  Fly   457 EWVGIISEYFHSAFGIVLFVLLVL 480
                    :|.|...:||..|..:
Zfish  1096 --------FFISESSVVLAYLFTI 1111

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
adgrl2aXP_021335387.1 Gal_Lectin 61..141 CDD:307994
OLF 155..411 CDD:321983
HormR 482..545 CDD:214468
GAIN 555..776 CDD:318649
GPS 800..851 CDD:197639
7tm_GPCRs 860..1141 CDD:333717 53/284 (19%)
TM helix 1 863..887 CDD:320095 3/15 (20%)
TM helix 2 896..917 CDD:320095 5/30 (17%)
TM helix 3 927..949 CDD:320095 6/21 (29%)
TM helix 4 968..984 CDD:320095 3/15 (20%)
TM helix 5 1003..1026 CDD:320095 7/24 (29%)
TM helix 6 1074..1099 CDD:320095 7/43 (16%)
TM helix 7 1103..1128 CDD:320095 3/9 (33%)
Latrophilin 1140..1520 CDD:308136
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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