DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and adgrl1a

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_021330394.1 Gene:adgrl1a / 562531 ZFINID:ZDB-GENE-131127-267 Length:1524 Species:Danio rerio


Alignment Length:321 Identity:58/321 - (18%)
Similarity:112/321 - (34%) Gaps:96/321 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   193 CLYRHNF-------DSDFPKSM---------WIIRHRCTSHISPGSLEILIITMICFVLTIAVYL 241
            |.:..||       :.|:|..|         |:           |    ::|:::|..:.|:.:.
Zfish   826 CSHLTNFAVLMVHHEPDYPGRMHELILFVITWV-----------G----IVISLVCLAICISTFC 875

  Fly   242 YIKKL---RNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGI--------CSPAGYSSHFFRMASN 295
            :::.|   ||...|.:          |:.:.:..|..|.||        |.......|||.:|:.
Zfish   876 FLRGLQTDRNTIHKNL----------CINLFIAELLFLIGIDKTQYHIACPIFAGLLHFFFLAAF 930

  Fly   296 LWLSVISYHTWKVLTSLNRVD---PNYRFL---RYNAFVWSTAAIMTGSIYIVNQIWENDPSKWN 354
            .|:.:.....:.:|..:...:   ..|.:|   .:.|.|...:|.:....|        ...|..
Zfish   931 SWMCLEGIQLYLMLVEVFESEYSRKKYYYLCGYCFPALVVGISAAIDYRSY--------GTKKAC 987

  Fly   355 WLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINC 419
            ||.:..:.          :|.:| ||...:...|:....:|...:.:....:    ..:..|:: 
Zfish   988 WLRVDNYF----------IWSFI-GPVSFIIMLNLVFLMITLHKMIRNSSAL----KPDSSRLD- 1036

  Fly   420 INFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEWVGIISEYFHSAF----GIVLFV 476
             |..|.. |..:.|..::||||.|.:        :|.....:|..|..:.|    |:.:|:
Zfish  1037 -NIKSWA-LGAIALLFLLGLTWAFGL--------LFINENTVIMAYLFTTFNAFQGMFIFI 1087

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804 7/36 (19%)
adgrl1aXP_021330394.1 Gal_Lectin 48..128 CDD:307994
OLF 142..398 CDD:321983
HormR 474..535 CDD:214468
GAIN 545..765 CDD:318649
GPS 789..836 CDD:197639 3/9 (33%)
7tmB2_Latrophilin-1 849..1106 CDD:320673 52/298 (17%)
TM helix 1 851..876 CDD:320673 5/39 (13%)
TM helix 2 885..907 CDD:320673 6/31 (19%)
TM helix 3 916..943 CDD:320673 5/26 (19%)
TM helix 4 955..975 CDD:320673 4/19 (21%)
TM helix 5 992..1021 CDD:320673 6/39 (15%)
TM helix 6 1037..1064 CDD:320673 10/35 (29%)
TM helix 7 1068..1093 CDD:320673 5/20 (25%)
Latrophilin 1105..1524 CDD:308136
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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