DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and adgrg6

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_001356058.1 Gene:adgrg6 / 561970 ZFINID:ZDB-GENE-041014-357 Length:1208 Species:Danio rerio


Alignment Length:409 Identity:83/409 - (20%)
Similarity:146/409 - (35%) Gaps:123/409 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 FTYMDLQ--ARVPLTDMAIIRDEFFDCDEMIYISDFNYFLEEVSIQIFNKCGLIVWFQDGKFWVT 182
            ||..:||  .|:.:..:...:|....|    ...|||         :.|..|  .|..||     
Zfish   732 FTIKNLQDPVRIEIAHLEYQKDPNPQC----VFWDFN---------LQNYSG--GWNSDG----- 776

  Fly   183 VDLFMEKQDYCLYRHNFDSDFPKSMWIIRHRCTSHIS-----PGSLEIL------IITMICFV-- 234
                      |  :...||:..:::.:..|  .:|..     ..:.|::      ::|.|.::  
Zfish   777 ----------C--KVGSDSNSNRTVCLCNH--LTHFGILMDVSRAAELIDEKNNRVLTFITYIGC 827

  Fly   235 --------LTIAVYLYIKKL-RNVTGKCIVCCIVSRFIQCLIMILDHLNLLNG---------ICS 281
                    .|:..|:..:|| |:...|.::....|      ::.|:.:.||:|         :|.
Zfish   828 GISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTS------LLFLNMVFLLDGWLASYEIKELCV 886

  Fly   282 PAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQ-- 344
            ......|||.:.|..|:.:.|.|.:..|..:.........|::....|...|.:.|.:..|::  
Zfish   887 TVAVFLHFFLLTSFTWMGLESIHMYIALVKVFNTYIRRYILKFCIVGWGVPAAIVGIVLAVSKDS 951

  Fly   345 IWEN---------DPSKWNWL--PLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIY 398
            ..:|         ..|::.|:  |:|.::.|..         |.|    .:...|||||.:..|.
Zfish   952 YGKNYYGKGKDGQGTSEFCWILNPVVFYVTCVA---------YFS----IIFLMNVAMFIVVMIQ 1003

  Fly   399 IRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEW--VGI 461
            |....|..:..|..|:...|..:..|.|:|        :|:||.|          .|:.|  |.:
Zfish  1004 ICGRNGKRSNRTLREDILRNLRSVVSLTFL--------LGMTWGF----------AFFAWGPVSL 1050

  Fly   462 ISEY----FHSAFGIVLFV 476
            ...|    |:|..|:.:||
Zfish  1051 AFMYLFTIFNSLQGLFIFV 1069

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804 19/95 (20%)
adgrg6NP_001356058.1 CUB 41..146 CDD:278839
LamG 153..336 CDD:354964
GPS 756..801 CDD:334696 14/78 (18%)
7tmB2_GPR126 816..1086 CDD:320662 62/291 (21%)
TM helix 1 818..843 CDD:320662 4/24 (17%)
TM helix 2 853..875 CDD:320662 5/27 (19%)
TM helix 3 886..913 CDD:320662 7/26 (27%)
TM helix 4 928..944 CDD:320662 3/15 (20%)
TM helix 5 975..998 CDD:320662 9/35 (26%)
TM helix 6 1021..1046 CDD:320662 9/42 (21%)
TM helix 7 1050..1075 CDD:320662 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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