DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and ADGRD2

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_001382354.1 Gene:ADGRD2 / 347088 HGNCID:18651 Length:982 Species:Homo sapiens


Alignment Length:268 Identity:46/268 - (17%)
Similarity:92/268 - (34%) Gaps:84/268 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   256 CCIVSRFIQCLIMILD-------HLNLLNGICSPAGY-------------------SSHFFRMAS 294
            |.:.:.|:..|:..:.       |.||...:.|..|:                   :.||..:.:
Human   708 CALTTTFLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKANEVACVAVTVAMHFLFLVA 772

  Fly   295 NLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWS--------TAAIMTGSIYIVNQIWENDPS 351
            ..|:.|.....|:.:.::: :.|......|:|..|.        |.|::..........|.|..:
Human   773 FSWMLVEGLLLWRKVVAVS-MHPGPGMRLYHATGWGVPVGIVAVTLAMLPHDYVAPGHCWLNVHT 836

  Fly   352 KWNWLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFA-LTAIYIRKVKGGINKFTNEEEG 415
            .                   ::|.:: ||.|.:.|.|..:.| :..|.:...:......:.:.  
Human   837 N-------------------AIWAFV-GPVLFVLTANTCILARVVMITVSSARRRARMLSPQP-- 879

  Fly   416 RINCINFDSQTYLQF-------LRLSIVMGLTWIFNVIPYSARLHIFWEW----VGIISEYFHSA 469
               |:  ..|.:.|.       |.|..|:||||:..::     :|:...|    ||:     :|.
Human   880 ---CL--QQQIWTQIWATVKPVLVLLPVLGLTWLAGIL-----VHLSPAWAYAAVGL-----NSI 929

  Fly   470 FGIVLFVL 477
            .|:.:|::
Human   930 QGLYIFLV 937

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
ADGRD2NP_001382354.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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