Protein Alignment mthl7 and mthl14

DIOPT Version :9

• Sequence 1: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_728509.1
• Gene: mthl14 / 318046
• FlyBaseID: FBgn0052476
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 112/581 - (19%)
• Similarity: 201/581 - (34%)
• Gaps: 222/581 - (38%)

  Fly    18 NNSNADIPGCNYY--DTVDISYIERQNDSYLYDDIEIP-------ASLTGYYEFRQFG------- 66
            |||:......|.:  ||.:.:.|: ..|:.::..:.:|       |:::|    .:|.
  Fly    29 NNSSKGSNNSNIFHEDTFNSTSID-VLDASIHSTLVVPQTYSTEAATISG----ARFATSVPVQS 88

  Fly    67 --DGSITPI-----EKHLRACVCSVRPCIRICCPAKNFL-------ANGKCDDGLKEELARFKPY 117
              |..:.|.     ||:.:..|.:....:|.|||....|       ::..||:|    |..|:|.
  Fly    89 PVDNPLDPADCSQREKYRKQPVATPSSRLRKCCPHGENLNIYRENQSDSMCDNG----LLSFEPT 149

  Fly   118 IYFTYM------DLQARVPL-------TDMAIIRDEFFDCDEMIYISDFNYFLEEVSIQIFNKCG 169
            |....:      ||:....|       .:.:::.|   |.|::.::      |::.|:.|.:|.|
  Fly   150 IISAVLFDNCIEDLEVETTLDYDIGNPCNSSLLYD---DKDDVFFV------LQDGSLLIIDKFG 205

  Fly   170 LIVWFQDGKFWVTVDLFMEKQDYCLYRHNFDSDFPKSMWIIRHRCTSHISPG--------SLEIL 226
                         .:.:..|:.|||       |..||..:....|.:.:...        ...::
  Fly   206 -------------NESYTVKEHYCL-------DIDKSGHLFAFTCVTQVEEQIAFAKVVFVAVLM 250

  Fly   227 IITMICFVLTIAVYLYIKKLRNVTGKCIVCCIVSRFIQCLIMILDHLNL-LNGICSPAGYSSHFF 290
            :|:|.|.:|...:::.::.|||:.|                     |:| |..:|..:||..|
  Fly   251 LISMPCLLLVSYLHMTLRLLRNLHG---------------------LSLSLMSLCLASGYFVH-- 292

  Fly   291 RMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRY-------NAFVWSTAAIMTGSIYIVNQIWEN 348
                    ||:  |.:.:        ||..|:.|       :.|.|.........:.:
  Fly   293 --------SVV--HIYGI--------PNQGFIGYVIQFCILSYFFWYLCICFNVLLNV------- 332

  Fly   349 DPSKWNWLPLVGFIRCSVKDWHP------SVWIYISGPS--LAL--------------------- 384
                  |..|...|:|| |.|..      :|:.: |||:  :||
  Fly   333 ------WYKLPCCIQCS-KSWATFNFACYAVFAF-SGPATIVALTVQKGLPGMPSYFLQGLTESI 389

  Fly   385 -----------STFNVAMFALTAIY---IRKVKGGINKFTNEEEGRINCINFDSQTYLQFLR--- 432
                       ||.....|.|..|.   .:::.|......|.:|.:  |: ||.|.|....:
  Fly   390 RDSQRYFIPPVSTILFLSFLLNIISFFGFQRISGYAKAEKNIQERK--CL-FDQQKYEDVKKDAK 451

  Fly   433 ----LSIVMGLTWIFNVIPYSARLHIFWEWVGIISEYF------HSAFGI-VLFVLLVLKR 482
                |.|:|.::|:..:|.:         :.|..|.|.      :...|: ||.:.||::|
  Fly   452 CVSLLGIIMVVSWLLEIITF---------YSGSNSNYLILCDMVNGLQGVWVLLIFLVVRR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	44/229 (19%)
mthl14	NP_728509.1	7tmB3_Methuselah-like	239..512	CDD:320167	64/333 (19%)
		TM helix 1	241..266	CDD:320167	4/24 (17%)
		TM helix 2	275..297	CDD:320167	10/54 (19%)
		TM helix 3	306..331	CDD:320167	3/24 (13%)
		TM helix 4	349..369	CDD:320167	5/20 (25%)
		TM helix 5	389..418	CDD:320167	5/28 (18%)
		TM helix 6	445..472	CDD:320167	5/35 (14%)
		TM helix 7	477..502	CDD:320167	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462174
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840