DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and Adgrg6

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_218313.7	Gene:	Adgrg6 / 308376	RGDID:	1308551	Length:	1248	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	105/512 - (20%)
Similarity:	170/512 - (33%)	Gaps:	148/512 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IPGCNYYDTVDISYIERQNDSYLYDDIEIPASLTGYYEFRQFGDGSITPIEKHLRACVCSVRPCI 88
            :||.|......|. :...||||...|.|               :|...|:..
  Rat   685 MPGTNAPSNFSIG-LPSNNDSYFQMDFE---------------NGQADPLAS------------- 720

  Fly    89 RICCPAKNFLANGKCDDGLKEELARFKPYIYFTYMDLQARVPLTDMAIIRDEFFDCD-------- 145
             :..| .|.|.|...:|.:   |.|...:.:|....|...|. :...|:......|.
  Rat   721 -VILP-PNLLENLSPEDSI---LVRRAQFTFFNKTGLFQDVG-SQRKILVSYVMACSIGNITIQN 779

  Fly   146 --EMIYISDFNYFLEEVSIQIFNKCGLIVWFQDGKFWVTVDLFMEKQ------DYCLYRHNFDSD 202
              :.:.|...:...:||...|   |.         ||   ||...|.      ..|: .|: |||
  Rat   780 LKDPVQIKIKHTRTQEVHQPI---CA---------FW---DLNQNKSFGGWNTSGCV-AHS-DSD 827

  Fly   203 FPKSMWIIRH-----------RCTSHISPGSLEILI--------ITMICFVLTIAVYLYIKKLRN 248
            ..:::.:..|           |..|.|...:.::|.        |:.|....|:..|:..:|||.
  Rat   828 AGETICLCNHFTHFGVLMDLPRSASQIDGRNTKVLTFITYIGCGISAIFSAATLLTYVAFEKLRR 892

  Fly   249 VTGKCIVCCIVSRFIQCLIMILDHLNLL------------NGICSPAGYSSHFFRMASNLWLSVI 301
                    ...|:.:..|...|..|||:            .|:|:......|||.:|:..|:.:.
  Rat   893 --------DYPSKILMNLSSALLFLNLIFLLDGWITSFGVAGLCTAVAALLHFFLLATFTWMGLE 949

  Fly   302 SYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIV----NQIW--------ENDPSKWN 354
            :.|.:..|..:.....:...|::....|...|::. ||.:|    |:::        ::|...|.
  Rat   950 AIHMYIALVKVFNTYIHRYILKFCIIGWGLPALVV-SIILVSRKQNEVYGKESYGKDQDDEFCWI 1013

  Fly   355 WLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINC 419
            ..|:|.::.|             :|....:...|||||.:..:.|....|..:..|..||...|.
  Rat  1014 QDPVVFYVSC-------------AGYFGIMFFLNVAMFIVVMVQICGRNGKRSNRTLREEVLRNL 1065

  Fly   420 INFDSQTYLQFLRLSIVMGLTWIFNV-------IPYSARLHIFWEWVGIISEYFHSA 469
            .:..|.|:|        :|:||.|..       ||:.....||....|:....||.|
  Rat  1066 RSVVSLTFL--------LGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCA 1114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	38/213 (18%)
Adgrg6	XP_218313.7	CUB	38..146	CDD:238001
		LamG	178..337	CDD:304605
		GPS	799..844	CDD:280071	13/61 (21%)
		7tm_4	861..1108	CDD:304433	59/276 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810