DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mthl7 and ADGRE2

DIOPT Version :10

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_054176753.1 Gene:ADGRE2 / 30817 HGNCID:3337 Length:892 Species:Homo sapiens


Alignment Length:319 Identity:66/319 - (20%)
Similarity:120/319 - (37%) Gaps:102/319 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 RCTSHISPGSLEILI---------------------ITMICFVLTIAVYLYIKKLRNVTGKCIVC 256
            ||| |:|  |..:|:                     ::::|.:|....:|..|.::|.:      
Human   582 RCT-HLS--SFAVLMAHYDV
QEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTS------ 637

  Fly   257 CIVSRFIQ-CLIMILDHLNLLNGI--------CSPAGYSSHFFRMASNLWLSVISYHTWKVLTSL 312
              .|..:| .|.:.|.||..|..|        ||....:.|:..:|:..|:.:.:.:.:  ||:.
Human   638 --TSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLF--LTAR 698

  Fly   313 NRVDPNY----RFLRYNAFVWS------TAAIMTGS---IYIVNQIWENDPSKWNWL-PLVGFIR 363
            |....||    ||::...|...      |.||...|   :|       ..||:. || |..||| 
Human   699 NLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLY-------GTPSRC-WLQPEKGFI- 754

  Fly   364 CSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYL 428
                      |.:: ||..|:.:.|:.:|.:| ::|.|             .|::.:|.:..|..
Human   755 ----------WGFL-GPVCAIFSVNLVLFLVT-LWILK-------------NRLSSLNSEVSTLR 794

  Fly   429 QFLRLS-------IVMGLTWIFNVIPYSARLHIFWEWVGIISEYFHSAFGIVLFVLLVL 480
            ....|:       .::|.||...::.......:    :..:....:|..|:.:|::..|
Human   795 NTRMLAFKATAQLFILGCTWCLGILQVGPAARV----MAYLFTIINSLQGVFIFLVYCL 849

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity