DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrf3

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_006239862.1 Gene:Adgrf3 / 298857 RGDID:1305868 Length:992 Species:Rattus norvegicus


Alignment Length:466 Identity:70/466 - (15%)
Similarity:154/466 - (33%) Gaps:196/466 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 LQARVP---------------LTDMAI--------------IRDEFFDCDEMIYISDFNYFLEEV 160
            ||||:|               :|.:|:              :||..:....||.:         :
  Rat   554 LQARIPWHSLAPLVLNGTNVRITSLALQKLDSRLPSNYRQGLRDTSYATPGMILV---------I 609

  Fly   161 SIQIFNKCGLIVWFQDGKFWVTVDLFMEKQD-----YCLY-RHN-FDSDFPKSMW---------- 208
            ||.           .||:.:...::.|:.:|     :|:: .|| |..   :..|          
  Rat   610 SIT-----------ADGQDFTQAEVIMDFEDMNGTLHCVFWDHNAFQG---RGGWSDEGCELQAA 660

  Fly   209 -------IIRH------RCTSHISPGS--LEIL---------IITMICFVLTIAVYLYIKKLRNV 249
                   :.||      ..:.|..|..  |::|         :..::|.|:...|:..:  :||.
  Rat   661 NASAVQCVCRHLTAFSILMSQHAVPEDPLLDLLSQVGVGASILALLVCLVIYRLVWRVV--VRNK 723

  Fly   250 TG--------KCIVCCIVSRFIQCLIMILDHLNLLNGICSPAGYSS----------HFFRMASNL 296
            ..        ..::|.:|:.  .|         .|.....|:||.|          |||.:|:..
  Rat   724 VAFFRHTALFNMVICLLVAD--TC---------FLGNPWLPSGYHSLVCLATAFLCHFFYLATFF 777

  Fly   297 WL---SVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPL 358
            |:   :::..|.                                .:::.:|:  :.|...:.:.:
  Rat   778 WMLAQALVLAHQ--------------------------------LLFVFHQL--SKPLVLSMMSI 808

  Fly   359 VGFIRCSVKDWHPSVWIY-------------ISGPSLALSTFNVAMFALTAI--------YIRKV 402
            :|:: |.:.....::.:|             :||..::|..|:..:.|:.::        .::.:
  Rat   809 LGYL-CPLGFAGVTLGLYLPQRKYLREGKCLLSGDGVSLHAFSEPVLAIVSVNGLVLVIAVLKLL 872

  Fly   403 KGGINK--FTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEWVGIISEY 465
            :..:::  ...:.:..:..:.       ..|.|:.:.||||...|........:| .::.:|   
  Rat   873 RPSLSEGPAVEKRQALVGVLK-------ALLILTPIFGLTWGLGVTTLFEGSLVF-HYIFVI--- 926

  Fly   466 FHSAFGIVLFV 476
            .:|..|:.:||
  Rat   927 LNSLQGVFIFV 937

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804 24/147 (16%)
Adgrf3XP_006239862.1 HRM 353..>395 CDD:295297
GPS 632..679 CDD:197639 7/49 (14%)
7tm_4 687..935 CDD:304433 42/306 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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