DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrf5

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_038938942.1 Gene:Adgrf5 / 245977 RGDID:621679 Length:1426 Species:Rattus norvegicus


Alignment Length:301 Identity:54/301 - (17%)
Similarity:109/301 - (36%) Gaps:87/301 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 PGSLEILIITMICF------VLTIAVYLYIKKL------RNVTGKCIVCCIVSRFIQCLIMILD- 271
            ||||..:::.:|.:      ::::|..|.::.:      :|.|......|||:  |...::|.| 
  Rat  1084 PGSLLKILLDIISYIGLGFSIVSLAACLVVEAMVWKSVTKNRTSYMRHICIVN--IALCLLIADI 1146

  Fly   272 -----------HLNLLNGICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYR--FLR 323
                       |..|....|..|.:..|||.::...|:..:....:            ||  |:.
  Rat  1147 WFIVAGAIHDGHYPLNETACVAATFFIHFFYLSVFFWMLTLGLMLF------------YRLIFIL 1199

  Fly   324 YNAFVWSTAAI--------------MTGSIYIVNQIWENDPSKW-NWLPLVGFIRCSVKDWHPSV 373
            ::|...:..||              :|..:....:::....:.| ||......:..::       
  Rat  1200 HDASKSTQKAIAFSLGYGCPLIISSITVGVTQPQEVYMRKNACWLNWEDTRALLAFAI------- 1257

  Fly   374 WIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLR----LS 434
                  |:|.:...||   ::|.:.|.|:   :.....::.|:     .:..:..|..:    |:
  Rat  1258 ------PALIIVVVNV---SITVVVITKI---LRPSVGDKPGK-----QEKSSLFQISKSIGVLT 1305

  Fly   435 IVMGLTWIFNVIPY----SARLHIFWEWVGIISEYFHSAFG 471
            .::||||.|.:...    :|..||.:..:......|...||
  Rat  1306 PLLGLTWGFGLATVIQGSNAVFHIIFTLLNAFQGLFILLFG 1346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
Adgrf5XP_038938942.1 FR3 592..622 CDD:409353
Ig strand E 602..608 CDD:409353
Ig strand F 616..623 CDD:409353
CDR3 623..632 CDD:409353
GPS 1029..1076 CDD:396408
7tm_GPCRs 1090..1363 CDD:421689 50/295 (17%)
TM helix 1 1091..1116 CDD:410628 3/24 (13%)
TM helix 2 1131..1153 CDD:410628 6/23 (26%)
TM helix 3 1167..1190 CDD:410628 5/22 (23%)
TM helix 4 1210..1226 CDD:410628 1/15 (7%)
TM helix 5 1248..1271 CDD:410628 4/38 (11%)
TM helix 6 1295..1320 CDD:410628 7/24 (29%)
TM helix 7 1325..1350 CDD:410628 6/22 (27%)
SEA 181..273 CDD:396113
IG 298..372 CDD:214652
Ig_3 548..621 CDD:404760
FR1 548..567 CDD:409353
Ig strand A 548..551 CDD:409353
Ig strand A' 555..557 CDD:409353
Ig strand B 561..568 CDD:409353
CDR1 568..575 CDD:409353
Ig strand D 591..598 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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