DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrg2

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_006528869.1 Gene:Adgrg2 / 237175 MGIID:2446854 Length:1092 Species:Mus musculus


Alignment Length:313 Identity:57/313 - (18%)
Similarity:118/313 - (37%) Gaps:86/313 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 CT-SHIS-------------PGSLEILIITMICFV----------LTIAVYLYIKKL-RNVTGKC 253
            || ||::             |.| :::.:|.|.::          :|:..|:..:|: |:...|.
Mouse   676 CTCSHLTSFGILLDLSRTSLPPS-QMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKI 739

  Fly   254 IVCCIVSRFIQCLIMILDH-LNLLN--GICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRV 315
            ::....:..:..||.:||. :.|.|  |.|.......|:|.:.|..|:.:.::|.:..|..:...
Mouse   740 LIQLCAALLLLNLIFLLDSWIALYNTRGFCIAVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNT 804

  Fly   316 DPNYRFLRYNAFVWSTAAIMTGSIYIVN----------QIWENDPSKWNWLPLVGFIRCSVKDWH 370
            ......|::....|...|::...:..::          :.....|..:.|:             :
Mouse   805 YIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGSYGKFPNGTPDDFCWI-------------N 856

  Fly   371 PSVWIYIS--GPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLR- 432
            .:|..||:  |....:...||:||.:..:.:.::|            :...:....:|.:|.|| 
Mouse   857 SNVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIK------------KKKQLGAQRKTSIQDLRS 909

  Fly   433 ---LSIVMGLTWIFNVIPYSARLHIFWEW--VGIISEYFHSAF----GIVLFV 476
               |:.::|:||.|          .|:.|  |.:...|..:.|    |..:|:
Mouse   910 IAGLTFLLGITWGF----------AFFAWGPVNVTFMYLFAIFNTLQGFFIFI 952

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804 57/313 (18%)
Adgrg2XP_006528869.1 Atrophin-1 <288..>423 CDD:367360
PRK14948 <368..559 CDD:237862
GPS 637..687 CDD:366827 4/10 (40%)
7tmB2_GPR64 700..969 CDD:320560 51/288 (18%)
TM helix 1 703..727 CDD:320560 4/23 (17%)
TM helix 2 737..758 CDD:320560 4/20 (20%)
TM helix 3 770..792 CDD:320560 4/21 (19%)
TM helix 4 812..828 CDD:320560 2/15 (13%)
TM helix 5 858..881 CDD:320560 7/22 (32%)
TM helix 6 904..929 CDD:320560 9/34 (26%)
TM helix 7 933..958 CDD:320560 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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