DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrf5

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_006524187.1 Gene:Adgrf5 / 224792 MGIID:2182928 Length:1406 Species:Mus musculus


Alignment Length:301 Identity:53/301 - (17%)
Similarity:110/301 - (36%) Gaps:87/301 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 PGSLEILIITMICF------VLTIAVYLYIKKL------RNVTGKCIVCCIVSRFIQCLIMILDH 272
            ||||..:::.:|.:      ::::|..|.::.:      :|.|......|||:  |...::|.|.
Mouse  1064 PGSLLKILLDIISYIGLGFSIVSLAACLVVEAMVWKSVTKNRTSYMRHICIVN--IAFCLLIADI 1126

  Fly   273 LNLLNG------------ICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYR--FLR 323
            ..::.|            .|..|.:..|||.::...|:..:....:            ||  |:.
Mouse  1127 WFIVAGAIHDGRYPLNETACVAATFFIHFFYLSVFFWMLTLGLMLF------------YRLIFIL 1179

  Fly   324 YNAFVWSTAAI--------------MTGSIYIVNQIWENDPSKW-NWLPLVGFIRCSVKDWHPSV 373
            ::|...:..||              :|..:....:::....:.| ||......:..::       
Mouse  1180 HDASKSTQKAIAFSLGYGCPLIISSITVGVTQPQEVYMRKNACWLNWEDTRALLAFAI------- 1237

  Fly   374 WIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLR----LS 434
                  |:|.:...||   ::|.:.|.|:   :.....::.|:     .:..:..|..:    |:
Mouse  1238 ------PALIIVVVNV---SITVVVITKI---LRPSIGDKPGK-----QEKSSLFQISKSIGVLT 1285

  Fly   435 IVMGLTWIFNVIPY----SARLHIFWEWVGIISEYFHSAFG 471
            .::||||.|.:...    :|..||.:..:......|...||
Mouse  1286 PLLGLTWGFGLATVIQGSNAVFHIIFTLLNAFQGLFILLFG 1326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
Adgrf5XP_006524187.1 IG 301..375 CDD:214652
ig 535..608 CDD:365836
GPS 1009..1056 CDD:366827
7tm_GPCRs 1070..1343 CDD:391938 49/295 (17%)
TM helix 1 1071..1096 CDD:341315 3/24 (13%)
TM helix 2 1111..1133 CDD:341315 6/23 (26%)
TM helix 3 1147..1170 CDD:341315 5/22 (23%)
TM helix 4 1190..1206 CDD:341315 1/15 (7%)
TM helix 5 1228..1251 CDD:341315 4/38 (11%)
TM helix 6 1275..1300 CDD:341315 7/24 (29%)
TM helix 7 1305..1330 CDD:341315 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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