DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and ADGRF2

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001355044.1	Gene:	ADGRF2 / 222611	HGNCID:	18991	Length:	708	Species:	Homo sapiens

Alignment Length:	278	Identity:	64/278 - (23%)
Similarity:	108/278 - (38%)	Gaps:	70/278 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 ISPGSLEILIITMICFV------------LTIAVYLY-------IKKLRNVTGKCIVCCIVSRFI 263
            :||..||.||:|.|.:|            |:|.|.::       |..||:|       |||:  |
Human   436 MSPHILESLILTYITYVGLGISICSLILCLSIEVLVWSQVTKTEITYLRHV-------CIVN--I 491

  Fly   264 QCLIMILD----HLNLLNGI------CSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPN 318
            ...:::.|    ..:.|:|.      |..|.:..|||      :|||..:...|.|..|..:...
Human   492 AATLLMADVWFIVASFLSGPITHHKGCVAATFFVHFF------YLSVFFWMLAKALLILYGIMIV 550

  Fly   319 YRFLRYNAFVWSTAAIMTGSIYIVNQIW--ENDPSKWNWLPLVGFIR---CSVK-DWHPSVWIYI 377
            :..|..:..|.|..::..|....:..|.  ..:|.|       |::|   |.:. |...::..::
Human   551 FHTLPKSVLVASLFSVGYGCPLAIAAITVAATEPGK-------GYLRPEICWLNWDMTKALLAFV 608

  Fly   378 SGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWI 442
            . |:||:...|  :..:|.:.::..:..|.....:|...|..|:      .....|:.::||||.
Human   609 I-PALAIVVVN--LITVTLVIVKTQRAAIGNSMFQEVRAIVRIS------KNIAILTPLLGLTWG 664

  Fly   443 FNVIPY----SARLHIFW 456
            |.|...    |...||.:
Human   665 FGVATVIDDRSLAFHIIF 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804
ADGRF2	NP_001355044.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900