DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and lat-2

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001040724.1	Gene:	lat-2 / 173771	WormBaseID:	WBGene00002252	Length:	1338	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	56/267 - (20%)
Similarity:	112/267 - (41%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 ITMICFVLTIAVYLYIKKLRNVTGK-----CIVCCIVSRFIQCLIMILDHLNLLNGICSPAGYSS 287
            |:::|..|::.|:.:.:.|:||...     |: |.:::..:  .::.:|......| |.......
Worm   907 ISIVCLALSVCVFTFFRNLQNVRNSIHRNLCL-CLLIAELV--FVIGMDRTGNRTG-CGVVAILL 967

  Fly   288 HFFRMASNLWLSVISYHTWKVLTSLNRVDPN-YRFLRYNAFVWSTAAIMTGSIYIVNQIWEN--- 348
            |:|.::|..|:.:..|..:.:|..:  .:|| .|...|..|.:.|.|::......:.  ||:
Worm   968 HYFFLSSFCWMLLEGYQLYMMLIQV--FEPNRTRIFLYYLFCYGTPAVVVAISAGIK--WEDYGT 1028

  Fly   349 DPSKWNWLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEE 413
            |...|            :....|::|.::: |.:.:...|: :|.|.|:   ||...:......:
Worm  1029 DSYCW------------IDTSTPTIWAFVA-PIIVIIAANI-IFLLIAL---KVVLSVQSRDRTK 1076

  Fly   414 EGRINCINFDSQTYLQFLR----LSIVMGLTWIFNVI-PYSARLHIFWEWVGIISEYFHSAFGIV 473
            .|||          :.:|:    |..::|:||||..: .........:.|:..|   .:...||.
Worm  1077 WGRI----------IGWLKGSATLLCLLGITWIFGFLTAVKGGTGTAFAWIFTI---LNCTQGIF 1128

  Fly   474 LFVLLVL 480
            :|||.|:
Worm  1129 IFVLHVV 1135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804
lat-2	NP_001040724.1	CLECT	52..193	CDD:214480
		Gal_Lectin	242..322	CDD:280328
		CLECT	330..>399	CDD:295302
		HormR	479..542	CDD:214468
		GAIN	556..>660	CDD:293098
		GPS	837..884	CDD:197639
		7tm_4	894..1129	CDD:304433	52/259 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840