DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and ADGRF3

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001138640.1	Gene:	ADGRF3 / 165082	HGNCID:	18989	Length:	1079	Species:	Homo sapiens

Alignment Length:	211	Identity:	40/211 - (18%)
Similarity:	76/211 - (36%)	Gaps:	43/211 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 ICSPAGYSSHFFRMASNLWL----SVISYHTWKVLTSL--NRVDPNYRFLRYNAFVWSTAAIMTG 337
            :|..|.:..||..:|:..|:    .|:::....|...|  :||.|....|.|...: ..|.:..|
Human   840 LCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPL-GLAGVTLG 903

  Fly   338 SIYIVNQIWENDPSKWNWLPLVGFIR---CSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYI 399
            .                :||...::|   |.:.....:::.:: ||.||:...|..:.|:..:.:
Human   904 L----------------YLPQGQYLREGECWLDGKGGALYTFV-GPVLAIIGVNGLVLAMAMLKL 951

  Fly   400 RKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEWVGIISE 464
            .:..........:.:..:..|.       ..|.|:.:.||||       ...|....|.|..:..
Human   952 LRPSLSEGPPAEKRQALLGVIK-------ALLILTPIFGLTW-------GLGLATLLEEVSTVPH 1002

  Fly   465 YFHSAFGIV--LFVLL 478
            |..:....:  :|:||
Human  1003 YIFTILNTLQGVFILL 1018

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804
ADGRF3	NP_001138640.1	HRM	431..477	CDD:280888
		GPS	713..758	CDD:280071
		7tm_4	770..1016	CDD:304433	37/207 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810