DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and Adgrg1

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_006530743.1 Gene:Adgrg1 / 14766 MGIID:1340051 Length:718 Species:Mus musculus


Alignment Length:272 Identity:55/272 - (20%)
Similarity:104/272 - (38%) Gaps:70/272 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 IITMICFVLTIAVYLYI-KKLRNVTGKCIVCCIVSRFIQCLIMILDHLNLLNG---ICSPAGYSS 287
            :|:.:..|.|||.||.. :|.|:.|.|..:..:.:.|:..:..:|.....|.|   .|..:....
Mouse   443 VISALACVFTIAAYLCSRRKSRDYTIKVHMNLLSAVFLLDVSFLLSEPVALTGSEAACRTSAMFL 507

  Fly   288 HFFRMASNLWLSVISYHTWKVLTSL-NRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPS 351
            ||..:|...|:.:..|:.::::..: ....|.| .|:.:...|.....:...:.:|:..      
Mouse   508 HFSLLACLSWMGLEGYNLYRLVVEVFGTYVPGY-LLKLSIVGWGFPVFLVTLVALVDVN------ 565

  Fly   352 KWNWLPLVGFIR-----------CSVKDWHPSVWIYISGPSL--ALSTFNVAMFALTAIYIRKVK 403
              |:.|::..:|           |.::|   |:..|::...|  .:..||:||.|...:.|.:::
Mouse   566 --NYGPIILAVRRTPERVTYPSMCWIRD---SLVSYVTNLGLFSLVFLFNLAMLATMVVQILRLR 625

  Fly   404 GGINKFTNEEEGRINCINFDSQTY---LQFLRLSIVMGLTW------------------IFNVI- 446
            .                  .||.:   |..|.||:|:||.|                  :|::| 
Mouse   626 P------------------HSQNWPHVLTLLGLSLVLGLPWALVFFSFASGTFQLVILYLFSIIT 672

  Fly   447 PYSARLHIFWEW 458
            .:...|...|.|
Mouse   673 SFQGFLIFLWYW 684

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
Adgrg1XP_006530743.1 PLL 60..193 CDD:376013
GAIN_A 204..251 CDD:376045
GPS 376..419 CDD:366827
7tm_GPCRs 431..698 CDD:391938 55/272 (20%)
TM helix 1 433..458 CDD:341315 6/14 (43%)
TM helix 2 468..490 CDD:341315 3/21 (14%)
TM helix 3 501..528 CDD:341315 5/26 (19%)
TM helix 4 541..561 CDD:341315 2/19 (11%)
TM helix 5 592..621 CDD:341315 8/28 (29%)
TM helix 6 629..656 CDD:341315 9/26 (35%)
TM helix 7 662..687 CDD:341315 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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